Maximizing the Clinical Utility of Next Generation Sequencing

The most comprehensive information you can get is both, because once again, we had seen separate primaries where they're completely discorded.

Maximizing the clinical utility and performance of cytology samples ...

Comprehensive molecular profiling by next generation sequencing (NGS) has revolutionized tumor classification and biomarker evaluation.

Clinical Utility of Next-Generation Sequencing-Based Panel Testing ...

The NGS assay should be performed earlier in the clinical course to maximize the clinical benefit. Broader reimbursement for the NGS assay ...

Maximizing the potential of high-throughput next-generation ...

High-throughput next generation sequencing (NGS) has significantly contributed to the field of genomics; however, further improvements can ...

Enhancing Clinical Utility: Utilization of International Standards and ...

Metagenomic sequencing has emerged as a transformative tool in infectious disease diagnosis, offering a comprehensive and unbiased approach to pathogen ...

Optimizing FDA's Regulatory Oversight of Next Generation ...

Optimizing FDA's Regulatory Oversight of Next Generation Sequencing Diagnostic ... clinical validity of human genomic variants; http://iccg.org/about-the ...

Best practices for the interpretation and reporting of clinical whole ...

Whole genome sequencing (WGS) shows promise as a first-tier diagnostic test for patients with rare genetic disorders.

Yield and Clinical Utility of Next-Generation Sequencing in Selected ...

Next-generation sequencing is available for assessing genomic alterations in non–small-cell lung cancer (NSCLC), although the performance characteristics and ...

Clinical Validation of a Targeted Next-Generation Sequencing Panel ...

Next-generation sequencing (NGS) is increasingly being applied to delineate the complex nature of these malignancies and identify high-value ...

Diagnostic and clinical utility of whole genome sequencing ... - Nature

The advances in next-generation sequencing (NGS) technology largely surmount these issues and have ushered in a new era for disease-gene ...

Clinical utility of custom-designed NGS panel testing in pediatric ...

Here, we report the laboratory validation and clinical utility of a large cohort of clinical NGS somatic sequencing results in diagnosis, ...

A Targeted High-Throughput Next-Generation Sequencing Panel for ...

Clinical next-generation sequencing (NGS) assay choice requires careful consideration of panel size, inclusion of appropriate markers, ability to detect ...

Clinical utility of metagenomic next-generation sequencing in fever ...

Metagenomic next-generation sequencing (mNGS) is a novel diagnostic tool increasingly used in the field of infectious diseases.

Next-Generation Sequencing to Guide Clinical Trials - AACR Journals

In addition, there is a rapid development of commercial vendors that perform genomic characterization of patients' tumor samples on a fee-for- ...

Clinical Utility of Next-generation Sequencing in Real-world Cases

Background/aim: Targeted next-generation sequencing (NGS) is a well-established technique to detect pathogenic alterations in tumors.

Clinical Sequencing Evidence-Generating Research (CSER)

CSER is uniquely positioned to answer questions about the clinical implementation of genomic sequencing to meet its growing use in the clinical ...

Optimization of a microfluidics-based next generation sequencing ...

The clinical standard of care for many advanced solid and hematologic malignancies currently requires mutation analysis of several genes in the ...

Lung Cancer

fusions is needed to maximize clinical utility. Materials and ... Discordance between two next-generation sequencing (NGS) assays for plasma cell-free DNA.

Benefits of integrating targeted next-generation sequencing (NGS ...

To meet this demand, targeted next-generation sequencing (NGS) panels are useful in clinical settings for accurate tumor profiling and the ...

MolDX: Next-Generation Sequencing for Solid Tumors - CMS

If yes, Clinical Validity and Clinical Utility must be described. Comment: Questions #1 and #2 appear to be an attempt to clearly distinguish NGS-based tests ...