Measurement of Epidermal Growth Factor Receptor|Derived Signals ...

Measurement of Epidermal Growth Factor Receptor-Derived Signals ...

The epidermal growth factor (EGF) receptor (EGFR) is an important regulator of cell growth, proliferation, survival, migration, and metabolism.

Measurement of Epidermal Growth Factor Receptor-Derived Signals ...

The epidermal growth factor (EGF) receptor (EGFR) is an important regulator of cell growth, proliferation, survival, migration, ...

Measurement of Epidermal Growth Factor Receptor-Derived Signals ...

EGF binding to EGFR triggers the activation of the receptor's intrinsic kinase activity, in turn eliciting the recruitment of many secondary signaling proteins ...

Measurement of epidermal growth factor receptor turnover ... - PubMed

Ligand-induced degradation represents an essential component of the overall regulation of EGF receptor (EGFR)-coupled signal transduction.

Regulation of Epidermal Growth Factor Receptor Signaling by ...

To directly evaluate EGFR signaling during receptor trafficking, we developed a technique to rapidly and selectively isolate internalized EGFR ...

Quantification of Short Term Signaling by the Epidermal Growth ...

Reported K d values for EGF binding to the solubilized extracellular domain of the receptor (40, 41) range from 100 to 500 nm, whereas full-length EGFR in ...

Epidermal Growth Factor Receptor - an overview - ScienceDirect.com

Epidermal Growth Factor Receptor (EGFR) is a type of receptor found in cells that is involved in normal growth and is closely related to other receptors in the ...

Epidermal growth factor receptor cascade prioritizes the ... - Nature

To experimentally verify this theoretical conclusion, we measured the STR of the epidermal growth factor (EGF)-related cascade in A431 skin ...

Epidermal growth factor receptor signaling: Current Biology

The epidermal growth factor receptor (EGFR) is a long known, versatile signal transducer that has been well conserved during evolution.

A comprehensive pathway map of epidermal growth factor receptor ...

The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important pathways that regulate growth, survival, proliferation, ...

Epidermal growth factor receptor signaling intensity determines ...

High-level expression of epidermal growth factor receptor (EGFR) can transform NIH 3T3 cells, and is frequently observed in human glioma, because of gene ...

The Epidermal Growth Factor Receptor Pathway: A Model for ...

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase receptor that is frequently expressed in epithelial tumors.

Early signaling dynamics of the epidermal growth factor receptor

We treated MCF-10A cells with EGF and measured tyrosine phosphorylation levels from 0 to 80 s on hundreds of sites in the cell. Examining ...

An Integrated Model of Epidermal Growth Factor Receptor ...

Our simulations predict that when EGFR is activated with TGF-α, receptor activation is biased toward the cell surface whereas EGF produces a signaling bias ...

Epidermal growth factor receptor - Wikipedia

The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of ...

Epidermal Growth Factor Receptor Signaling in the Kidney

Signaling through epidermal growth factor (EGF) receptors (ErbB receptors; EGFRs) is important for fundamental cellular functions, ...

QuickGO::Term GO:0007173

The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands. 2012-04-01, Added ...

Bidirectional Signaling between the Estrogen Receptor and the ...

This includes heterodimerization between receptor family members, exemplified by the four members of the epidermal growth factor (EGF) receptor (EGFR) family ( ...

Epidermal Growth Factor Receptor (EGFR) Signaling - Sigma-Aldrich

EGFR is expressed in many organs and aberrant expression is implicated in various cancers. This review highlights various signaling components of EGFR pathway ...

Comprehensive Model for Epidermal Growth Factor Receptor ...

The epidermal growth factor (EGF) receptor (EGFR) undergoes ligand-dependent dimerization to initiate transmembrane signaling.