Measurement of apoptosis and proliferation of bone marrow plasma ...

The median plasma cell apoptotic index (PCAI) for patients with monoclonal gammopathy of undetermined significance (MGUS), smouldering or indolent myeloma (SMM/ ...

Measurement of apoptosis and proliferation of bone marrow plasma cells in patients with plasma cell proliferative disorders. THOMAS E. WITZIG, MICHAEL TIMM ...

Measurement of apoptosis and proliferation of bone marrow plasma ...

The proliferative rate of malignant plasma cells, as measured by the plasma cell labelling index (PCLI), is an important prognostic factor in multiple ...

Combining Measurements of Plasma Cell Apoptosis and ...

We have previously shown that the % bone marrow plasma cells in apoptosis (PCAP) determined by a flow cytometry method that uses Annexin V staining or 7 ...

Combined Measurement of Plasma Cell Proliferation and Apoptosis ...

The proliferative activity of myeloma plasmocytes in bone marrow aspirate was measured by flow- cytometry using propidium-iodide index (PC-PI), ...

Combined Measurement of Plasma Cell Proliferation and Apoptosis ...

The proliferative activity of myeloma plasmocytes in bone marrow aspirate was measured by flow- cytometry using propidium-iodide index (PC ...

A model of hematopoietic bone marrow apoptosis during growth ...

While cell proliferation results in the development of various tissues and organs, cellular death leads to refinement of the various tissues and ...

British Journal of Haematology | Wiley Online Library

The aims of this study were to develop a flow cytometric method to measure the apoptosis index of fresh marrow plasma cells and develop a plasma ...

(PDF) Measurement of apoptosis and proliferation of bone marrow ...

The plasma cell proliferative index (PCPI), determined by a slide technique or by flow cytometry, detects cells in the S phase of the cell cycle and is a useful ...

Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to ... - MDPI

Proliferation and apoptosis ... analysis of bone marrow plasma cells. Blood 2007 ... proliferation of bone marrow plasma cells in patients with plasma cell ...

The potential of proliferative and apoptotic parameters in clinical ...

The reviewed studies clearly recognize the importance of proliferation and apoptotic mechanisms in the pathogenesis of bone marrow (BM) ...

Understanding heterogeneity of human bone marrow plasma cell ...

lived plasma cells results in resistance to apoptosis ... Integra- · tive analysis ... proliferation · and drug resistance in the bone marrow ...

Modulation of Apoptosis Pathways in the Biology and Treatment of ...

Adhesion of multiple myeloma cells to bone marrow stromal cells initiates secretion of soluble factors like interleukin-6 and tumour necrosis ...

Bone marrow stroma inhibits proliferation and apoptosis in leukemic ...

Morphological analysis of stromal–leukemic cell line cocultures showed similarity to primary long-term BM cultures. Leukemic cells infiltrated ...

Proliferation is a central independent prognostic factor and target for ...

Measurement of apoptosis and proliferation of bone marrow plasma cells in patients with plasma cell proliferative disorders. Br J Haematol ...

Measurement of myeloma cell apoptosis in co-cultures. Cells gated ...

Multiple myeloma (MM) is a neoplastic proliferation of bone marrow plasma cells. PRL-3 is a phosphatase induced by interleukin (IL)-6 and other growth ...

Study on Tim3 Regulation of Multiple Myeloma Cell Proliferation via ...

... apoptosis of tumor cells (18). MM is a malignant blood system tumor characterized by massive proliferation of monoclonal plasma cells in bone marrow.

Apoptotic Extracellular Vesicles Ameliorate Multiple Myeloma by ...

Staurosporine (STS) was used to induce apoptosis of murine bone marrow MSCs. Then apoEVs were isolated using a sequential certification system ...

USP15 inhibits multiple myeloma cell apoptosis through activating a ...

... bone marrow-derived plasma cells, was also measured. ... assay (e, f) ... proliferation and apoptosis, NF-κBp65 expression was also measured.

Plasma Cell Survival Is Mediated by Synergistic Effects of Cytokines ...

Purification of bone marrow plasma cells. A, FACS analysis of IgG-1-secreting bone marrow cells after MACS enrichment. Bone marrow cell suspensions were ...