Mechanism of human rhinovirus infections

Mechanism of human rhinovirus infections - PMC

HRVs enter from the apical side of the cells lining the airways by receptor-mediated endocytosis via LDLR and ICAM-1.

Mechanism of Rhinovirus Immunity and Asthma - Frontiers

Rhinovirus infects airway epithelial cells representing the first line of defense, inducing innate and adaptive immune responses. Initially, RV ...

Mechanism of human rhinovirus infections - PubMed

About 150 human rhinovirus serotypes are responsible for more than 50 % of recurrent upper respiratory infections. Despite having similar 3D ...

Rhinovirus (RV) Infection (Common Cold) - Medscape Reference

Pathogenesis of rhinovirus infection ... The attachment of the virus to its receptors (ICAM-1, CHDR-3, low-density lipoprotein receptor [LDLR]) in ...

Human Rhinovirus - an overview | ScienceDirect Topics

The two strains of HRVs are A, B, and the new strain C was discovered. Mostly they cause respiratory infection in humans, and responsible for common cold [17].

T-helper 2 mechanisms involved in human rhinovirus infections and ...

We focus on the immune responses that might skew a T-helper type 2 response, including alarmins, in those with allergic asthma.

Human Rhinovirus - an overview | ScienceDirect Topics

In part because of this, rhinovirus infection is limited to the upper respiratory tract, and rhinoviruses almost never cause lower respiratory tract infections.

Human Rhinoviruses | Clinical Microbiology Reviews - ASM Journals

Humoral immune responses are important for preventing HRV infection, although the precise mechanism is unknown. HRV infection in antibody-naïve ...

Rhinovirus: A Narrative Review on Its Genetic Characteristics ...

Discovered in the 1950s, human rhinoviruses (HRVs) are mostly known as the leading cause of the “common cold”; they are ubiquitous, and HRV infections occur ...

Mechanism of human rhinovirus infections

Human rhinoviruses (HRVs) account for more than 50 % of upper respiratory tract infections. The disease is known as the common cold that usually resolves within ...

How does rhinovirus cause the common cold cough?

(B) Human rhinovirus infection in airway epithelial cells. There are two main ways that HRV causes physical disruption of airway barriers, ...

Human rhinovirus promotes STING trafficking to replication ... - Nature

Although HRV is an RNA virus, we investigated whether there was interferon-β (IFN-β) production in response to HRV infection in ALI cells. It ...

Respiratory Consequences of Rhinovirus Infection - JAMA Network

The human rhinoviruses are divided into 2 groups based on cellular receptors. More than 90% of rhinovirus serotypes attach to the host cell via intercellular ...

Mechanism of human rhinovirus infections | springermedizin.de

Summary and conclusions. HRVs are a major cause of respiratory infections of infants. The numerous serotypes are precluding the development of a vaccine, and ...

T-helper 2 mechanisms involved in human rhinovirus infections and ...

Human rhinovirus (HRV) is the most common causative agent for the common cold and its respiratory symp- toms. For those with asthma, cystic fibrosis, ...

(PDF) Mechanism of human rhinovirus infections - ResearchGate

We found that even rhinovirus serotypes binding the same receptor can travel along different endocytic pathways and release their RNA genome into the cytosol ...

Host immune responses to rhinovirus: Mechanisms in asthma

Infection of epithelial cells generates a variety of proinflammatory mediators to attract inflammatory cells to the airway with a subsequent worsening of ...

Human Rhinovirus Infection Blocks Severe Acute Respiratory ...

Human rhinovirus triggers an innate immune response that blocks severe acute respiratory syndrome coronavirus 2 replication within human respiratory epithe.

Antiviral Therapeutic Approaches for Human Rhinovirus Infections

RV infection does, however, compromise epithelial barrier integrity which may cause an increased translocation of pathogens and complications of respiratory ...

Infantile respiratory syncytial virus and human rhinovirus infections

HRV is a highly diverse group of viruses that affect subjects of all ages, is ubiquitous and occurs year-round. In contrast to RSV, infections with HRV cause ...