Mechanisms for size|dependent protein segregation at immune ...

Mechanisms for Size-Dependent Protein Segregation at Immune ...

These molecular rulers show how membrane-bending elasticity can drive size-dependent exclusion of proteins within immune synapses.

Mechanisms for size-dependent protein segregation at immune ...

Immunological synapses are specialized intercellular contacts formed by several types of immune cells in contact with target cells or ...

Mechanisms for size-dependent protein segregation at immune ...

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Mechanisms for Size-Dependent Protein Segregation at Immune ...

Request PDF | Mechanisms for Size-Dependent Protein Segregation at Immune Synapses Assessed with Molecular Rulers | Immunological synapses ...

Mechanisms for Size-Dependent Protein Segregation ... - NASA ADS

NASA/ADS · Mechanisms for Size-Dependent Protein Segregation at Immune Synapses Assessed with Molecular Rulers.

Mechanisms for size-dependent protein segregation at immune ...

Mechanisms for size-dependent protein segregation at immune synapses assessed with molecular rulers. Juha Matti Alakoskela, Apurba L. Koner, Dominika ...

Size-Dependent Segregation Controls Macrophage Phagocytosis of ...

In order to isolate the mechanism of FcγR signaling in macrophages, we reconstituted a minimal model of an antibody-opsonized target-cell ...

Mechanisms for size-dependent protein segregation at immune ...

Mechanisms for size-dependent protein segregation at immune synapses assessed with molecular rulers. Immunological synapses are specialized intercellular ...

Size-dependent protein segregation at membrane interfaces

... One potential mechanism that could explain the reduction of LD proteins is that the LD surface is somehow occluded, preventing protein trafficking to or ...

Size-dependent protein segregation creates a spatial switch for ...

These observations suggest two mechanisms by which cadAJs might influence Notch signaling: first, cadAJs recruit γ-secretase; second, cadAJs ...

Modulation of Immune Responses by Particle Size and Shape

(A) Dendritic cells (DC), macrophages (MF), and neutrophils (NE) of the immune system encounter particles with different physical properties (size, shape, ...

Size-dependent protein segregation at membrane interfaces.

In the immunological synapse, it has been suggested that exclusion of the non-binding protein CD45 is driven by a size-dependent mechanism, since CD45 isoforms ...

Cluster size regulates protein sorting in the immunological synapse

These results demonstrate that cluster size directly influences protein spatial positioning in the T cell IS. We discuss a sorting mechanism, ...

Size-dependent segregation controls macrophage phagocytosis of ...

Cell biologists have seen fit to describe many cell behaviors without recourse to the precise protein interactions through which they occur. A frustrating gap ...

Boltzmann Energy-based Image Analysis Demonstrates that ... - PLOS

However, the mechanism by which these proteins segregate remains unclear; one key hypothesis is a redistribution based on protein size. Simulations of this ...

The immune synapse clears and excludes molecules above a size ...

Here, we establish that the synapse does not completely seal the synaptic cleft, but rather excludes extracellular molecules in a size-dependent ...

Plasma membrane segregation during T cell activation

Segregation of the plasma membrane into distinct domains is an essential element of immune cell activation in response to the engagement of immunoreceptors.

Cluster size regulates protein sorting in the immunological synapse

These results demonstrate that cluster size directly influences protein spatial positioning in the T cell IS. We discuss a sorting mechanism, based on ...

Dimensions and Interactions of Large T-Cell Surface Proteins

The first step of the adaptive immune response involves the interaction of T cells that express T-cell receptors (TCRs) with peptide-loaded ...

Boltzmann energy-based image analysis demonstrates that ... - Ebsco

... protein size. Simulations of this mechanism ... dependent exclusion, and further ... size differences explain protein segregation at immune synapses.