Mechanosensing and the Hippo Pathway in Microglia

Mechanosensing and the Hippo Pathway in Microglia - PubMed

In this review, we examine evidence for the potential involvement of Hippo pathway components specifically in microglia in the pathogenesis of Alzheimer's ...

Mechanosensing and the Hippo Pathway in Microglia: A Potential ...

Current evidence suggests that the Hippo pathway and YAP have important roles in microglia in the pathogenesis of AD. AD, Alzheimer's disease; ...

Mechanosensing and the Hippo Pathway in Microglia: A Potential ...

2. Department of Chemistry and Pharmaceutical Sciences, Kingston University London, Kingston-upon-Thames KT1 2EE, UK. ORCIDs linked to this ...

Mechanosensing and the Hippo Pathway in Microglia - OUCI

The activation of microglia, the inflammatory cells of the central nervous system (CNS), has been linked to the pathogenesis of Alzheimer's disease and ...

Innate sensing of mechanical properties of brain tissue by microglia

Mechanosensing and the hippo pathway in microglia: A potential link to alzheimer's disease pathogenesis? 2021, Cells. Inhibition of microglial receptor ...

The Hippo signalling pathway and its implications in human health ...

... signal transmission between mechanical cues and the Hippo pathway cascade. ... Differential reactions of microglia to brain metastasis of ...

Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo ...

How these polarity cues are linked to mechanical signals that act on the Hippo pathway ... microglial reactivity following activation by ...

An update on the role of Hippo signaling pathway in ischemia ...

Mechanosensing and the hippo pathway in microglia: a potential link to Alzheimer's disease pathogenesis? Cells, 10 (11) (2021), p. 3144, 10.3390 ...

Emerging roles of the Hippo signaling pathway in modulating ...

Mechanosensing and the hippo pathway in microglia: a potential link to alzheimer's disease pathogenesis? Cells. 2021; 10: 3144. 10.3390 ...

Hippo/YAP Pathway Plays a Critical Role in Effect of GDNF Against ...

We suggest that the Hippo pathway is worth investigating as a mechanosensing pathway in microglia, and could be one potential therapeutic ...

Biochemical Pathways of Cellular Mechanosensing ... - MDPI

... Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer's Disease Pathogenesis? Cells 2021, 10, 3144. [Google Scholar] [CrossRef] ...

The roles of Hippo/YAP signaling pathway in physical therapy - Nature

... mechanical signals and regulated by Hippo/YAP signaling pathway [34]. ... microglia. Evid Based Complemen Alternat Med. 2020;2020:8163052 ...

Matrix stiffness-dependent microglia activation in response to ...

Stolinski and F. E. Mackenzie, Mechanosensing and the hippo pathway in microglia: A potential link to Alzheimer's Disease pathogenesis?, Cells, ...

The emerging role of Hippo signaling in neurodegeneration

It is suggested that the Hippo pathway is worth investigating as a mechanosensing pathway in microglia, and could be one potential therapeutic target ...

The Role and Regulatory Mechanism of Hippo Signaling ... - Frontiers

... signaling and the Hippo-YAP pathway. ... Deficiency of MST1 in microglia significantly suppressed NF-κB signaling and microglial activation.

YAP Nuclear Localization in the Absence of Cell-Cell Contact Is ...

Codelia, V.A. ∙ Sun, G. ∙ Irvine, K.D.. Regulation of YAP by mechanical strain through Jnk and Hippo signaling. Curr. Biol. 2014; 24 ...

Mrs. Lucrezia Bruno | Author - SciProfiles

We suggest that the Hippo pathway is worth investigating as a mechanosensing pathway in microglia, and could be one potential therapeutic ...

Disease implication of hyper-Hippo signalling | Open Biology

Desmosome disruption results in changes of mechanical control of upstream regulators of the Hippo ... Hippo Pathway in Microglia: A Potential Link ...

Citations to Microglia in steady state - JCI

Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer's Disease Pathogenesis? L Bruno, S Karagil, A Mahmood, A ...

Matrix stiffness-dependent microglia activation in response to ...

regulation function of microglia in the mechanical ... Stolinski and F. E. Mackenzie, Mechanosensing and the hippo pathway in microglia: A potential link to ...