Mechanotransduction governs CD40 function and underlies X ...
Mechanotransduction governs CD40 function and underlies X ...
B cell maturation in germinal centers (GCs) depends on cognate interactions between the T and B cells. Upon interaction with CD40 ligand ...
Mechanotransduction governs CD40 function and underlies X ...
X-HIgM CD40L mutations impair catch bond formation, suppress endogenous tension, and reduce force-enhanced CD40 signaling, leading to ...
Mechanotransduction governs CD40 function and underlies X ...
Significantly, X-HIgM CD40L mutations impair catch bond formation, suppress endogenous tension, and reduce force-enhanced CD40 signaling, leading to ...
Mechanotransduction governs CD40 function and underlies X ...
To conclude, our findings establish that mechanical forces regulate the CD40–CD40L interaction and shed light on the mechanistic underpinnings ...
Mechanotransduction governs CD40 function and underlies X
Upon interaction with CD40 ligand (CD40L) on T cells, CD40 delivers co-stimulatory signals alongside B cell antigen receptor (BCR) signaling to ...
(PDF) Mechanotransduction governs CD40 function and underlies X ...
Abstract · mechanobiology of the CD40–CD40L system and whether mechanotransduction plays a role in · mechanotransduction in regulating CD40 signal output that ...
Mechanotransduction governs CD40 function and underlies X ...
Mechanotransduction governs CD40 function and underlies X-linked Hyper IgM syndrome ; Journal. bioRxiv (Cold Spring Harbor Laboratory) ; Published.
Waggoner Lab on X: "Unlocking the power of force, CD40 employs ...
Unlocking the power of force, CD40 employs mechanotransduction to fine-tune antibody-mediated immune responses @ScienceAdvances ...
Human CD40 Ligand / TNFSF5 Protein, Fc Tag, active trimer ...
Mechanotransduction governs CD40 function and underlies X-linked hyper-IgM syndrome. Choi, Travaglino, Münchhalfen et al. Sci Adv (2024) 10 (46), eadl5815.
Dr. Ankur K. Singh - Hematology Oncology - MediFind
Mechanotransduction governs CD40 function and underlies X-linked Hyper IgM syndrome. Mechanotransduction governs CD40 function and underlies X-linked Hyper ...
Mechanical Stiffness Controls Dendritic Cell Metabolism and Function
47. O'Connor, R.S. ∙ Hao, X. ∙ Shen, K. ... Substrate rigidity regulates human T cell activation and ...