Mendelian randomization analyses clarify the effects of height on ...

An inverse correlation between stature and risk of coronary artery disease (CAD) has been observed in several epidemiologic studies, ...

An inverse correlation between stature and risk of coronary artery disease (CAD) has been observed in several epidemiologic studies, and recent Mendelian ...

Mendelian randomization analyses clarify the effects of height on ...

An inverse correlation between stature and risk of coronary artery disease (CAD) has been observed in several epidemiologic studies, and recent ...

(PDF) Mendelian randomization analyses clarify the effects of height ...

We confirmed that a one standard deviation decrease in height (~6.5 cm) was associated with a 12.0% increase in the risk of CAD, consistent with previous ...

Mendelian randomization analyses clarify the effects of ... - PLOS

Multivariable MR including 12 additional cardiovascular disease risk factors as exposures attenuates the effect of height on coronary artery disease risk and ...

Mendelian randomisation analyses find pulmonary factors mediate ...

This causal association remains after performing sensitivity analyses relaxing pleiotropy assumptions. The causal effect of height on CAD risk ...

Mendelian randomization analyses reveal mediating factors of the ...

Mendelian randomization analyses reveal mediating factors of the causal effect of height on coronary artery disease ; Daniel Hui ; Christopher S.

Mendelian randomization estimates of the effects of taller height on...

The meta-analysis results from population and within-sibship Mendelian randomization analyses estimating the effect of taller height on biomarkers across UK ...

Taller height and risk of coronary heart disease and cancer - eLife

To conclude, using within-sibship Mendelian randomization, we showed that height has individual-level effects on risk of CHD and cancers as well ...

Mendelian randomization analysis on the impacts of age at ...

Ample evidence supports potential influence of age at menarche (AM) on adult height (AH), but multiple confounders may affect causal estimates.

Mendelian Randomization Analysis on the Impacts of Age at ...

Ample evidence supports potential influence of age at menarche (AM) on adult height (AH), but multiple confounders may affect causal estimates.

effect estimation and bias detection through Egger regression ...

Results: We illustrate the use of this approach by re-analysing two published Mendelian randomization studies of the causal effect of height on lung function, ...

Adult height, coronary heart disease and stroke - Oxford Academic

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

Height, body mass index, and socioeconomic status - The BMJ

Design Mendelian randomisation study to test for causal effects of differences in stature and BMI on five measures of socioeconomic status.

The effects of height and BMI on prostate cancer incidence and ...

We constructed genetic risk scores that summed each man's number of height and BMI increasing alleles across multiple single nucleotide ...

Avoiding dynastic, assortative mating, and population stratification ...

However, while Mendelian randomization estimates from samples of unrelated individuals suggested that taller height and lower BMI increase ...

Mendelian Randomization analysis of the causal effect of adiposity ...

Pleiotropy (Paaby and Rockman, 2013; Stearns, 2010) is the effect of a single SNP on multiple phenotypes (Lobo, 2008; Stearns, 2010). There would be no bias in ...

Reading Mendelian randomisation studies: a guide, glossary, and ...

Mendelian randomisation uses genetic variants, which are fixed at conception, to support causal inferences about the effects of modifiable risk ...

A bias-corrected multivariable Mendelian randomization method

However, for most traits, IVs in MVMR analyses explain a substantial portion of the variance, which will provide good power to detect causal effects. This is ...

Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney ...

However, the largest randomized clinical trial failed to find a protective effect of thiazides on kidney stone recurrence. Our mendelian ...