Metabolic cell death in cancer

Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis ...

Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell ...

Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis ...

This review discusses the mechanisms of metabolic cell death—ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis—and explores their ...

Crosstalk between metabolism and cell death in tumorigenesis

Many studies have successfully demonstrated that metabolism is inextricably linked to cell death of cancer cells.

Metabolism-regulated ferroptosis in cancer progression and therapy

Cancer cell metabolism is mainly composed of carbohydrate metabolism, amino acid metabolism and lipid metabolism, in which enzymes and ...

Crosstalk between metabolism and cell death in tumorigenesis

It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to such an abnormally rapid proliferation rate, ...

Cuproptosis: p53-regulated metabolic cell death? - Nature

Cuproptosis is a novel type of copper-induced cell death that primarily occurs in cells that utilize oxidative phosphorylation as the main metabolic pathway to ...

Metabolic cell death pathways could be novel therapeutic targets in ...

The review discusses how metabolic cell death, distinct from traditional forms of regulated cell death like apoptosis, ...

How does metabolism affect cell death in cancer? - Villa - FEBS Press

Here, we discuss recent insights showing how energetic metabolism may regulate cell death and how this might be relevant for cancer treatment.

Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis ...

Metabolic cell death in cancer | 647. Protein & Cell in ferroptosis regulation (Liu and Gu, 2022) Other tumor suppressors, such as BAP1 ...

Metabolic Regulation of Apoptosis in Cancer - ScienceDirect.com

In this article, we review how cellular apoptosis is regulated and how metabolism can influence the signaling pathways leading to apoptosis.

Cancer Metabolism and the Evasion of Apoptotic Cell Death - MDPI

Our review attempts to dissect a causal relationship between two cancer hallmarks, ie, deregulated cellular energetics and the evasion of programmed cell death.

Metabolic catastrophe as a means to cancer cell death

Metabolic catastrophe as a means to cancer cell death ... J Cell Sci (2007) 120 (3): 379–383. ... During tumorigenesis, normal growth mechanisms are ...

Targeting the Interplay between Cancer Metabolic Reprogramming ...

In this review we analyze the main metabolic differences between cancer and non-cancer cells and how these can affect the various cell death pathways.

Targeting Metabolism to Induce Cell Death in Cancer Cells and ...

Abstract. Abnormal metabolism and the evasion of apoptosis are considered hallmarks of cancers. Accumulating evidence shows that cancer stem ...

Inflammation and Metabolism in Cancer Cell—Mitochondria Key ...

As previously stated, cancer cells have a deregulated metabolic system and therapies that target glycolysis, pyruvate oxidation, and glutamine metabolism (e.g., ...

Modes of Regulated Cell Death in Cancer - AACR Journals

The intrinsic (mitochondrial) pathway serves to activate apoptosis as an appropriate response to various internal traumas, such as metabolic stress, hypoxia, ...

Cancer cell death using metabolic glycan labelling techniques

We describe a method for inducing cancer cell death, which relies on the use of a H 2 O 2 -responsive glycan metabolic precursor in conjunction with antibody- ...

The regulation of amino acid metabolism in tumor cell death

We have outlined the function of AA metabolism in tumor progression, the modalities of cell death, and the regulation of AA metabolism on tumor cell death in ...

Regulators mount up: the metabolic roles of apoptotic proteins

Apoptosis is a programmed cellular suicide mechanism with important roles in the maintenance of multicellular organisms. The classical intrinsic apoptotic ...

Metabolic Regulation of Cell Death | Proteintech Group

At times, cells need to die for the health of the organism. The programming responsible for this sacrificial cell death is called “Apoptosis”. It is regulated ...