Metabolic changes of Interleukin|12/15/18|stimulated human NK cells

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells

Natural Killer (NK) cells acquire memory-like properties following a brief stimulation with IL-12, IL-15 and IL-18.

Metabolic changes of Interleukin‑12/15/18‑stimulated human NK cells

In this paper, we have analyzed metabolic changes associated to IL-12/15/18-stimulation and the relevance of glycolytic pathway for NK cell effector functions.

IL-12/15/18-induced cell death and mitochondrial dynamics of ...

Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment. ... Metabolic changes of Interleukin-12/15/18-stimulated human NK ...

Metabolic regulation of NK cell function: implications for ... - NCBI

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells. Sci Rep. 2021;11(1):6472. doi: 10.1038/s41598-021-85960-6. [PMC free ...

Cytokine-Induced Memory-Like NK Cells: From the Basics to Clinical ...

Metabolic Changes of Interleukin-12/15/18-Stimulated Human NK Cells. Sci Rep (2021) 11:6472. doi: 10.1038/s41598-021-85960-6. PubMed Abstract ...

Advances in metabolic reprogramming of NK cells in the tumor ...

Metabolic plasticity of human T cells: preserved cytokine ... Metabolic changes of Interleukin-12/15/18-stimulated human NK cells.

Cytokine-induced natural killer cell training is dependent on cellular ...

... natural killer cell training is dependent on cellular metabolism ... F. Metabolic changes of interleukin-12/15/18-stimulated human NK cells.

Interleukin-18 up-regulates amino acid transporters and facilitates ...

Upon inflammation, natural killer (NK) cells undergo metabolic changes to support their high energy demand for effector function and proliferation.

Assessing NK Cell Bioenergetic Metabolism Using Extracellular Flux ...

A short, 18-hour overnight stimulation with IL12/15/18 did not change the level of this receptor. ... Interleukin-12/15/18-Stimulated Human NK Cells. Sci. Rep.

Amino acid-dependent cMyc expression is essential for NK cell ...

... NK cell metabolism and function. Similar content being viewed by others. Metabolic changes of Interleukin-12/15/18-stimulated human NK cells.

Metabolic Reprograming via Deletion of CISH in Human iPSC ...

Interleukin-15 (IL-15) stimulates multiple NK cell functions, including differentiation, proliferation, activation, and survival (Huntington et ...

Metabolic switch towards glycolysis of human IL-12/15/18-stimulated ...

Download scientific diagram | Metabolic switch towards glycolysis of human IL-12/15/18-stimulated NK cells. Bar charts representing (A) glucose analogue ...

[PDF] Activity of IL-12/15/18 primed natural killer cells against ...

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells · Medicine, Biology. Scientific Reports · 2021.

Proteomic and phenotypic characteristics of memory-like natural ...

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells. Sci Rep ... Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect.

Metabolic Reprogramming Supports IFN-γ Production by CD56 ...

To investigate whether human NK cells behave in similar fashion, we examined cellular metabolism in human primary NK cells in response to either IL-2 or IL-12/ ...

Differential IL-12 signaling induces human natural killer cell ...

In line with the mouse model, phenotypic changes in human NK cells ... A. Cerwenka . 2012 . Sustained effector function of IL-12/15/18- ...

IL-15-dependent immune crosstalk between natural killer cells and ...

... changes can prominently shape the cellular metabolism and functions of these cells. ... Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected ...

Expanding and Improving Natural Killer Cells for Adoptive ... - MDPI

Metabolic Changes of Interleukin-12/15/18-Stimulated Human NK Cells. Sci. Rep. 2021, 11, 6472. [Google Scholar] [CrossRef] [PubMed]; Lee, S.-H.; Fragoso ...

Cytokine-induced memory-like natural killer cells for cancer ...

Metabolic changes in CIML NK cells including glucose transporter ... Metabolic changes of Interleukin-12/15/18-stimulated human NK cells.

Immunometabolism of T cells and NK cells: metabolic control of ...

Natural Killer (NK) and T-lymphocytes have complementary roles in the defense against pathogens. However, studies of NK cell metabolism are only ...