Metabolic control of induced pluripotency

Metabolic control of induced pluripotency - Frontiers

In this review, we discuss the achievements in the current understanding of the molecular mechanisms of processes controlled by metabolic pathways.

Metabolic control of induced pluripotency - PubMed

Metabolic pathways and retrograde mitochondrial signals are involved in the regulation of various aspects of stem cell biology.

Metabolic control of induced pluripotency - PMC - NCBI

Among the main metabolic features of this process, representing a switch from the dominance of oxidative phosphorylation to aerobic glycolysis ...

Metabolic control of induced pluripotency - UC Library Search

Pluripotent stem cells of the mammalian epiblast and their cultured counterparts-embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs)-have the ...

Metabolic regulation in pluripotent stem cells - ScienceDirect.com

PSCs are obtained from preimplantation embryos as embryonic stem cells (ESCs), or by reprogramming of somatic cells as induced pluripotent stem ...

Cellular Metabolism and Induced Pluripotency - Cell Press

In addition to transcriptional and epigenetic remodeling, cellular reprogramming to pluripotency is also accompanied by a rewiring of metabolic ...

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

Significantly, relative nutrient availability impacts iPSC reprogramming efficiency, epigenetic regulation and cell fate, and differentially ...

Metabolic control of induced pluripotency - ResearchGate

Among the main metabolic features of this process, representing a switch from the dominance of oxidative phosphorylation to aerobic glycolysis ...

Energy Metabolism Regulates Stem Cell Pluripotency - Frontiers

Pluripotent stem cells (PSCs) are characterized by their unique capacity for both unlimited self-renewal and their potential to differentiate to all cell ...

The metabolome of induced pluripotent stem cells reveals metabolic ...

... into a new layer of regulation involved in inducing pluripotency, and in evaluating iPSC and ESC equivalence.

Perspective Metabolic Regulation in Pluripotent Stem Cells during ...

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have an unlimited capacity for ...

ERRs Mediate a Metabolic Switch Required for Somatic Cell ...

Cell metabolism is adaptive to extrinsic demands; however, the intrinsic metabolic demands that drive the induced pluripotent stem cell (iPSC) program ...

Metabolic remodeling during the loss and acquisition of pluripotency

The reverse process, when cells enter a pluripotent state through reprogramming, also requires an early metabolic switch to take place, as the ...

Metabolic regulation of pluripotency and germ cell fate through α ...

An intricate link is becoming apparent between metabolism and cellular identities. Here, we explore the basis for such a link in an in vitro model for early ...

Metabolic control of induced pluripotency - OUCI

Pluripotent stem cells of the mammalian epiblast and their cultured counterparts—embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs)—have the ...

Unveiling dynamic metabolic signatures in human induced ... - PLOS

We applied principles of process dynamics and control to human induced pluripotent stem cells (hiPSC) and human neural stem cells (hNSC) ...

Metaboloepigenetic Regulation of Pluripotent Stem Cells

The differentiation of pluripotent stem cells is associated with extensive changes in metabolism, as well as widespread remodeling of the ...

Metabolism in pluripotency: Both driver and passenger? - UCLA

New insights from recent studies on metabolic control of chromatin ... induced pluripotency. Cell 162, 412– 424 CrossRef Medline. 32 ...

15 - The metabolic framework of pluripotent stem cells and potential ...

The regulation of a number of pathways shown to be involved in ES cell maintenance and the continued expression of the core pluripotent stem-cell regulator by ...

Cellular metabolism and homeostasis in pluripotency regulation

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have the capacity to self-renew ...