Metabolic interactions between neurons and astrocytes

Neuronal-Astrocyte Metabolic Interactions - PubMed Central

Astrocytes are important in buffering neurons from the bloodstream, forming part of the blood-brain barrier (BBB) and hence assisting in providing glucose to ...

Astrocyte-neuron metabolic cooperation shapes brain activity

The paradigm of this biological feature is the astrocyte-neuron couple, in which the glycolytic metabolism of astrocytes contrasts with the ...

Functional metabolic interactions of human neuron-astrocyte 3D in ...

Here, we demonstrate the establishment of neuronal and astrocytic metabolic signatures and shuttles in a human 3D neural cell model, namely the glutamine- ...

Astrocyte metabolism and signaling pathways in the CNS - Frontiers

Although the metabolic functionalities of astrocytes are well known, their relationship to neurological disorders is poorly understood. The ways in which ...

Metabolic compartmentalization between astroglia and neurons in ...

Astroglia or astrocytes, the most abundant cells in the brain, are interposed between neuronal synapses and microvasculature in the brain ...

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic ...

This review focuses on the cellular aspects of brain energy metabolism, with a particular emphasis on the metabolic interactions between neurons and astrocytes.

Metabolic Interactions between Neurons and Astrocytes - SpringerLink

Metabolic interactions between neurons and glial cells can occur in at least two different ways, 1) transfer of a metabolite from a cell type, competent in ...

Neuron-Astrocyte Interactions: Partnership for Normal Function and ...

Interactions between neurons and astrocytes are critical for signaling, energy metabolism, extracellular ion homeostasis, volume regulation, and ...

1: Neuron and astrocyte metabolism - Medicine LibreTexts

Within the brain, astrocytes outnumber neurons but have reduced demand for ATP. Although astrocytes display lower oxidative rates when compared ...

Unraveling the complex metabolic nature of astrocytes - Frontiers

One of the important and early recognized metabolic function of astrocytes concerns the reuptake and recycling of the neurotransmitter glutamate ...

Modeling the Metabolic Interactions of Astrocytes and Neurons

As with glutamate, the astrocyte is charged with restoring the extracellular K+ concentration to. Page 6. Metabolic Interactions of Astrocytes and Neurons.

Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases

The metabolic interactions between astrocytes and neurons, astrocytes and microglia were also detailed discussed. Finally, we classified ...

Neuron–astrocyte metabolic coupling facilitates spinal plasticity and ...

Metabolic coupling between astrocytes and neurons has been implicated in neuronal plasticity and memory formation in the central nervous system, ...

Neuronal-astrocyte metabolic interactions - Scholars@Duke

Brain function depends on complex metabolic interactions among only a few different cell types, with astrocytes providing critical support for neurons.

Energy Metabolism of the Brain, Including the Cooperation between ...

Glycogenolysis and the uptake of K+ ions have been found to have a special mutual relationship in astrocytes [18]. It has been shown that in astrocyte cultures, ...

The consequences of neurodegenerative disease on neuron ...

Astrocytes are morphologically and phenotypically well-suited to the role of providing CNS metabolic and antioxidant support, demonstrating close interactions ...

Metabolic interactions between neurons and astrocytes: role in ...

Our research activities focus on the interactions between neurons and astrocytes, particularly as concerns the regulation of energy ...

METABOLIC INTERACTIONS BETWEEN NEURONS AND ...

NEURON. ASTROClTIE. Figure 5. Metabolic interactions between neurons and astrocytes. In both cell types the cytosol is indicated by light stippling and the ...

Metabolic switch in the aging astrocyte supported via integrative ...

Dysregulated central-energy metabolism is a hallmark of brain aging. Supplying enough energy for neurotransmission relies on the neuron-astrocyte metabolic ...

Brain Metabolism in Health and Neurodegeneration - MDPI

Astrocytes, which interface with neurons and blood vessels, play a crucial role in coordinating the brain's metabolic activity, and their dysfunction can have ...