Metabolic programming in dendritic cells tailors immune responses ...

In this review, we present the current knowledge on the intrinsic and extrinsic determinants of DC metabolism, how they regulate DC function with examples from ...

It is being increasingly acknowledged that immune cells depend on certain metabolic traits to perform their functions and that the extracellular environment ...

Metabolic regulation of dendritic cell activation and immune function ...

Dendritic cells (DCs) are antigen-presenting cells that bridge innate and adaptive immune responses. Multiple cell types, including DCs, ...

Metabolic programming in dendritic cells tailors immune responses ...

It is plausible that DC subsets modulate their stimulatory abilities in response to unique metabolic programming. The metabolic requirements of DCs are just ...

Dynamic metabolic reprogramming in dendritic cells - PubMed Central

Abstract. Infection with the influenza virus triggers an innate immune response that initiates the adaptive response to halt viral replication and spread.

Metabolic programming in dendritic cells tailors immune responses ...

AbstractIt is being increasingly acknowledged that immune cells depend on certain metabolic traits to perform their functions and that the extracellular ...

Reviews & Analysis | Cellular & Molecular Immunology - Nature

Metabolic programming in dendritic cells tailors immune responses and homeostasis. Sofie Hedlund Møller; Limei Wang; Ping-Chih Ho. Review ...

Immunometabolism of dendritic cells in health and disease

Dendritic cells (DCs) are crucial mediators that bridge the innate and adaptive immune responses. Cellular rewiring of metabolism is an emerging regulator ...

Metabolic Control of Dendritic Cell Functions: Digesting Information

Dendritic cells (DCs) control innate and adaptive immunity by patrolling tissues to gather antigens and danger signals derived from microbes and tissue.

DC Metabolism Controls Lung T Cell Polarization - ScienceDirect.com

Dendritic cells' metabolism determines their adjustment to specific tissues and the type of adaptive immunity they instruct following inflammatory ...

Metformin induces tolerogenicity of dendritic cells by promoting ...

Dendritic cells (DCs) can mediate immune responses or immune tolerance depending on their immunophenotype and functional status.

Metabolic sensor AMPK licenses CD103 dendritic cells to induce ...

Recently, it has become clear that immune cell activation and function, including that of DCs, ... Metabolic Program that Drives Dendritic Cell ...

Immunometabolism governs dendritic cell and macrophage function

Recent studies on intracellular metabolism in dendritic cells (DCs) and macrophages provide new insights on the functioning of these critical controllers of ...

The cancer metabolic reprogramming and immune response

The researchers found that tumors inhibited the function of tumor-infiltrating T cells through competitive uptake of glucose, even when there ...

Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic ...

Dendritic cell (DC) activation by Toll-like receptor (TLR) agonists causes rapid glycolytic reprogramming that is required to meet the ...

Toll-like receptor–induced changes in glycolytic metabolism ...

Toll-like receptor (TLR)–directed dendritic cell (DC) activation is critical for the tailoring of immune responses to specific pathogens.1,2 ...

Immune metabolism: a bridge of dendritic cells function

An increasing number of researches have shown that cell metabolism regulates cell function. Dendritic cells (DCs), a professional antigen ...

Metabolic adaptation of lymphocytes in immunity and disease

Dendritic cells (DCs) prime T cell-mediated immune responses for proper induction of antitumor immunity. Metabolic reprogram- ming is associated ...

Metabolic control of dendritic cell activation and function - Europe PMC

Dendritic cells (DCs) are key regulators of both immunity and tolerance by controlling activation and polarization of effector T helper cell and regulatory ...

The impact of metabolic reprogramming on dendritic cell function

Dendritic cells (DCs) are antigen-presenting cells with the ability to activate naïve T cells and direct the adaptive cellular immune response toward a ...