Metabolic regulation of aging and age|related disease

Metabolic regulation of aging and age-related disease - PMC

Dr. Mattson's work on metabolic regulation of aging and age-related disease recapitulates the developmental ontogeny of neural circuits, ...

Metabolic regulation of aging and age-related disease - PubMed

In this historical review, we highlight Dr. Mattson's many contributions to understanding neurobiological responses to physical exercise and dietary ...

Metabolic regulation of aging and age-related disease - ScienceDirect

The observation that healthy aging can be decoupled from widespread synaptic dysfunction led to broader inquiry into strategies to limit the negative impact of ...

Metabolic regulation of aging and age-related disease - ScienceDirect

In this historical review, we highlight Dr. Mattson's many contributions to understanding neurobiological responses to physical exercise and dietary ...

Aging and aging-related diseases: from molecular mechanisms to ...

A recent study found that a deficiency of melatonin, an endogenous free radical scavenger that decreases with age and neurodegeneration, impairs ...

Editorial: Advances in metabolic mechanisms of aging and its ...

Metabolic alterations are considered hallmarks of aging and age-related diseases. ... metabolism in aging, lifespan regulation, and age-related disease. Aging ...

Metabolic changes in aging humans: current evidence and ... - JCI

Aging is associated with increased adiposity, and the prevalence of obesity is increasing in the older adult population. Older adults who ...

Metabolic control of aging and metabolism - Nature

A range of metabolic alterations accumulate over time often setting off the path to compromised biological fitness and disease.

Metabolic diseases and healthy aging: identifying environmental ...

Aging is a significant risk factor for developing and progressing metabolic diseases in older adults due to various physiological changes that ...

Metabolism - Center for Healthy Aging - Colorado State University

Aging and Metabolism ... As we age, metabolic processes do not operate as well as when we were younger. Our bodies do not metabolize nutrients from food as ...

The metabolic regulation of aging | LCT

attempt to exploit the connection between aging and metabolism to treat a wide range of age-related diseases. Together, these insights are ...

Metabolic Control of Longevity: Cell

Multiple inborn defects in metabolic circuitries accelerate aging, whereas genetic loci linked to exceptional longevity influence metabolism.

The Critical Role of Metabolic Pathways in Aging | Diabetes

Aging is arguably the most universal contributor to the etiologies of metabolic decline and related diseases, including type 2 diabetes mellitus ...

Metabolism & Basic Biology of Aging

Complications of these processes include obesity, metabolic diseases, sarcopenia, frailty, cancer, and other age-related pathophysiology. The research will help ...

The biochemistry and cell biology of aging: metabolic regulation ...

Aging is characterized by increased risks for metabolic disorders, with age-associated degenerative diseases exhibiting varying degrees of mitochondrial ...

Metabolic Syndrome, Aging and Involvement of Oxidative Stress

Aging, the development of insulin resistance and cardiovascular disease seem to be accelerated in the metabolic syndrome [131-133]. It is generally considered ...

The role of lipid metabolism in aging, lifespan regulation, and age ...

Although lipids have been traditionally treated as detrimental and as simply associated with age-related diseases, numerous studies have shown ...

Molecular basis of ageing in chronic metabolic diseases

These are known as age-related diseases (ARDs) and include chronic metabolic disorders such as obesity, type 2 diabetes (T2D), and ...

Recent Progress in Metabolic Signaling Pathways Regulating Aging ...

Current evidence suggests that improved metabolic efficiency with reduced nutrient storage and enhanced fuel oxidation serves to combat age-related disease ...

Metabolic regulation of aging and age-related disease - ResearchGate

... Aging is an intricate process involving progressive functional degeneration at both the cellular and organ levels. Multiple factors, including nutrition, ...