Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells ...

However, induced pluripotent stem cells (iPSC) retain transcriptional memory, epigenetic memory, and metabolic memory from their somatic cells ...

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

The significance of metabolites during the reprogramming process is central to further elucidating how iPSC retain somatic cell characteristics and ...

Metabolic regulation in pluripotent stem cells - PubMed

Developmental progression of pluripotent cells can be paused, both in vitro and in vivo, in response to hormonal and metabolic alterations. Such ...

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) reta.

Metabolic regulation in pluripotent stem cells - ScienceDirect.com

Finally, metabolism is not simply regulated by exogenous stimuli or nutrient availability in PSCs, as key pluripotency regulators, such as Oct4, ...

Energy Metabolism Regulates Stem Cell Pluripotency - Frontiers

Pluripotent stem cells (PSCs) are characterized by their unique capacity for both unlimited self-renewal and their potential to differentiate to all cell ...

Metabolic remodeling during somatic cell reprogramming to induced ...

Induced pluripotent stem cells (iPSCs) were first established from differentiated somatic cells by gene introduction of key transcription ...

(PDF) Metabolism Is a Key Regulator of Induced Pluripotent Stem ...

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) retain ...

Metabolism in Pluripotent Stem Cells and Early Mammalian ...

Core pluripotency factors and developmental regulators reciprocally control the expression of key metabolism genes and their encoded pathways.

Perspective Metabolic Regulation in Pluripotent Stem Cells during ...

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have an unlimited capacity for ...

Metabolic Reprogramming of Stem Cell Epigenetics

For many years, stem cell metabolism was viewed as a byproduct of cell fate status rather than an active regulatory mechanism; however, there is now a ...

The metabolome of induced pluripotent stem cells reveals metabolic ...

Metabolism is vital to every aspect of cell function, yet the metabolome of induced pluripotent stem cells (iPSCs) remains largely ...

Metabolic control of induced pluripotency - Frontiers

The TCA cycle is critical for the regulation of cellular processes such as stem cell self-renewal, differentiation, and reprogramming through the regulation of ...

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) retain ...

Pluripotent stem cell energy metabolism: an update - EMBO Press

Recent studies link changes in energy metabolism with the fate of pluripotent stem cells (PSCs). Safe use of PSC derivatives in regenerative medicine ...

Metaboloepigenetic Regulation of Pluripotent Stem Cells

The differentiation of pluripotent stem cells is associated with extensive changes in metabolism, as well as widespread remodeling of the ...

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) retain ...

Metabolic Regulation of Cardiac Differentiation and Maturation in ...

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are expected to be useful for ...

Cellular metabolism and homeostasis in pluripotency regulation

Pluripotent stem cells (PSCs) can immortally self-renew in culture with a high proliferation rate, and they possess unique metabolic ...