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MicroRNA|22|3p ameliorates Alzheimer's disease by targeting ...


MicroRNA-22-3p ameliorates Alzheimer's disease by targeting ...

Our study showed that miR-22-3p could improve apoptosis and reduce Aβ deposition by acting on Sox9 through the NF-κB signaling pathway to ...

MicroRNA-22-3p ameliorates Alzheimer's disease by targeting ...

Studies have suggested that many down-regulated miRNAs identified in the brain tissue or serum of Alzheimer's disease (AD) patients were ...

Additional file 13 of MicroRNA-22-3p ameliorates Alzheimer's ...

Additional file 13 of MicroRNA-22-3p ameliorates Alzheimer's disease by targeting SOX9 through the NF-κB signaling pathway in the ...

MicroRNA-22-3p ameliorates Alzheimer's disease by targeting ...

Abstract Background Studies have suggested that many down-regulated miRNAs identified in the brain tissue or serum of Alzheimer's disease (AD) patients were ...

Additional file 10 of MicroRNA-22-3p ameliorates Alzheimer's ...

Additional file 10 of MicroRNA-22-3p ameliorates Alzheimer's disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus.

MiR-22-3p Regulates Amyloid β Deposit in Mice Model of ... - PubMed

... targeting and regulating MAPK14 expression, which ameliorated AD symptoms. Keywords: Alzheimer's disease; BACE1; MAPK14; MiR-22-3p; amyloid precursor ...

MicroRNAs: pioneering regulators in Alzheimer's disease ... - Nature

MicroRNA-149 is downregulated in Alzheimer's disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting ...

MicroRNAs in Alzheimer's disease: Potential diagnostic markers and ...

MicroRNA-149 is downregulated in Alzheimer's disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting BACE1. Genet ...

miR-23b-3p rescues cognition in Alzheimer's disease by reducing ...

miR-23b-3p ameliorates cognitive dysfunction in AD against tau hyperphosphorylation and neuronal apoptosis via directly targeting GSK-3β-mediated p-tau/Bax ...

A multi-targeting immunotherapy ameliorates multiple facets of ...

A multi-targeting immunotherapy ameliorates multiple facets of Alzheimer's disease in 3xTg mice ... and GSK-3β activity. Furthermore ...

MiR-22-3p Regulates Amyloid β Deposit in Mice Model of ...

MiR-22-3p Regulates Amyloid β Deposit in Mice Model of Alzheimer's Disease by Targeting Mitogen-activated Protein Kinase 14. Author(s): Qiling Ji* , Xuemei Wang ...

MicroRNAs in Alzheimer's Disease - Frontiers

MicroRNA-34c downregulation ameliorates amyloid-beta-induced synaptic failure and memory deficits by targeting VAMP2. J. Alzheimers Dis. 48, 673–686. doi ...

MicroRNA-22 (miR-22) Overexpression Is Neuroprotective ... - PLOS

miR-22 is an miRNA that has previously been shown to be downregulated in both HD and Alzheimer's disease brain [7], [10]. Using the miRNA target algorithm ...

Potential microRNA-related targets in clearance pathways of ...

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.

MicroRNA-149 is downregulated in Alzheimer's disease and inhibits ...

MicroRNA-149 is downregulated in Alzheimer's disease and inhibits β-amyloid accumulation and ameliorates neuronal viability through targeting BACE1.

MicroRNA-650 Regulates the Pathogenesis of Alzheimer's Disease ...

miR-650 targets the expression of three AD-associated components: Apolipoprotein E (APOE), Presenilin 1 (PSEN1), and Cyclin-Dependent Kinase 5 (CDK5).

Inhibition of miR-331-3p and miR-9-5p ameliorates ... - Theranostics

Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy ... Targeting miR-331-3p and miR-9-5p could ameliorate the ...

The Regulation of microRNAs in Alzheimer's Disease - Frontiers

MicroRNA-195 downregulates Alzheimer's disease amyloid-beta production by targeting BACE1. ... and tangles ameliorates cognitive deficits. PLoS ONE. (2011) ...

Targeting MicroRNA-485-3p Blocks Alzheimer's Disease Progression

... miR-485-3p ASO (Figure 3A–D), suggesting that miR-485-3p ASO ameliorated the Aβ burden. Insoluble Aβ 1–42 production also decreased in the cortex of 5XFAD ...

Insights into the Role of microRNAs as Clinical Tools for Diagnosis ...

... and ameliorates learning and memory in Alzheimer's disease. ... MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1.