MicroRNA|34a suppresses invasion through downregulation of ...

MicroRNA-34a suppresses invasion through downregulation of ...

By using gamma-secretase inhibitor (N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester) that interfered Notch signaling and RNA interference ...

MicroRNA-34a suppresses invasion through downregulation of ...

Our results provide evidence that miR-34a inhibits invasiveness through regulation of the Notch pathway and its downstream matrix degrading enzyme.

MicroRNA-34a suppresses invasion through downregulation of ...

Evidence is accumulating that miRNAs regulate cell invasion. In breast cancer, miR-21 promotes invasion and metastasis by suppressing the expression of ...

MicroRNA-34a suppresses breast cancer cell proliferation and ...

MicroRNA-34a suppresses breast cancer cell proliferation and invasion by targeting Notch1 ... downregulation through transfection with miR-34a mimic or ...

A first-in-class fully modified version of miR-34a with ... - Nature

... invasion as cells transfected with PM-miR-34a ... miR-34a inhibits cell proliferation in prostate cancer by downregulation of SIRT1 expression.

MicroRNA‑34a expression affects breast cancer invasion in vitro and ...

It has been recently reported that in liver cancer cell lines, miR-34a inhibits the expression of E2F1/E2F3 and results in the suppression of ...

Mir-34: A New Weapon Against Cancer? - ScienceDirect.com

RT Pang, CO Leung, TM Ye, W Liu, PC Chiu, KK Lam, et al. MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and ...

MicroRNA-34a: a potential therapeutic target in human cancer - Nature

... Lam KK et al. MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells.

MiRNA-34a reversed TGF-β-induced epithelial-mesenchymal ...

Downregulation of SMAD4 suppressed TGF-β-induced EMT, invasion, and migration. (A). TGF-β-induced morphological changes in CNE-1 cells were reversed by SMAD4 ...

MicroRNA-34 family: a potential tumor suppressor and therapeutic ...

MiR-34a/c-dependent PDGFR-alpha/beta downregulation inhibits ... Tumor suppressor microRNA-34a inhibits cell migration and invasion by ...

MicroRNA-34a Inhibits Uveal Melanoma Cell Proliferation ... - IOVS

MicroRNA-34a Inhibits Uveal Melanoma Cell Proliferation and Migration through Downregulation of c-Met ... Tumour invasion and metastasis initiated by microRNA-10b ...

Restoring microRNA-34a overcomes acquired drug resistance and ...

2C, miRNA-34a-5p inhibition resulted in a significant upregulation ... MicroRNA-34a suppresses breast cancer cell proliferation and invasion by ...

MicroRNA‑34a attenuates the proliferation, invasion and metastasis ...

miR‑34a acted as a tumor suppressor to inhibit gastric cancer proliferation and invasion via the downregulation of MET. Introduction. Gastric ...

MicroRNA-34a functions as an anti-metastatic microRNA and ...

... 34a could suppress ... suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells.

MicroRNA-34a suppresses invasion through downregulation ... - OUCI

MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells · Ronald T.K. Pang · Carmen O.N. ...

MiR-542-3p suppresses neuroblastoma cell proliferation and ...

In summary, miR-542-3p inhibited cell proliferation and invasion through the downregulation of KDM1A in neuroblastoma. Figure 5 The ...

Downregulation of HMGB1 by miR-34a is sufficient to suppress ...

While forced expression of miR-34a in CaCx and CRC cells inhibited HMGB1 mRNA and protein levels, proliferation, migration and invasion, ...

Downregulation of miR-654-3p in Colorectal Cancer Indicates Poor ...

... miR-654-3p inhibits tumor proliferation and invasion in CRC. miRNAs affect the malignant cell proliferation, migration and invasion ...

Capture of MicroRNA–Bound mRNAs Identifies the Tumor ... - PLOS

(2009) p53-independent upregulation of miR-34a during ... (2010) MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical ...

MicroRNA-34 Family in Cancers: Role, Mechanism, and Therapeutic ...

The downregulation of miR-34a promotes cancer progression by ... DNMT3B silencing suppresses migration and invasion by epigenetically promoting miR-34a in bladder ...