Mitochondrial function in peripheral blood cells across the human ...

Mitochondrial dysfunction is considered a hallmark of aging. Up to now, a gradual decline of mitochondrial respiration with advancing age ...

The main significant changes were an age-related relative decline in complex I-linked respiration and a corresponding rise of complex II-linked ...

[PDF] Mitochondrial function in peripheral blood cells across the ...

Mitochondrial function in peripheral blood cells across the human lifespan · J. Ehinger, Emil Westerlund, +4 authors. E. Elmér · Published in npj Aging 7 February ...

Existence of Circulating Mitochondria in Human and Animal ...

These findings suggested that the existence of circulating mitochondria in blood may function as a novel mediator for cell-cell communications and maintenance ...

Mitochondrial Function Maintained in Ageing Blood Cells

In this study, the largest to date, mitochondrial respiration in blood cells was largely intact throughout the human lifespan.

Mitochondrial function in peripheral blood cells across the human ...

The main significant changes were an age-related relative decline in complex I-linked respiration and a corresponding rise of complex II-linked respiration in ...

Correlation of mitochondrial respiration in platelets, peripheral blood ...

There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less ...

Mitochondrial function in peripheral blood cells across the human ...

Title. Mitochondrial function in peripheral blood cells across the human lifespan. Authors. Ehinger, Johannes K; Westerlund, Emil; Frostner, Eleonor Åsander ...

Mitochondrial function in peripheral blood cells across the human ...

In this study, we analyzed mitochondrial respiration in peripheral blood mononuclear cells (PBMCs) and platelets from 308 individuals across the human lifespan ...

The mitochondrial function of peripheral blood mononuclear cells in ...

The circulating cell-free mitochondrial DNA (ccf-mtDNA) levels, reflecting cellular stress and damage, were significantly increased in older frail and depressed ...

Mitochondrial function in peripheral blood cells across the human ...

Mitochondrial function in peripheral blood cells across the human lifespan ... In this study, we analyzed mitochondrial respiration in peripheral blood ...

Mitochondrial networking in human blood cells with application in ...

As there is increasing use of human blood cells as a proxy of organ mitochondrial function with respiration in various disease states, the addition of ...

Enhanced mitochondrial oxidative metabolism in peripheral blood ...

We and others have shown that an alteration of mitochondrial function in PBMCs is linked to the pathogenesis or development of a wide variety of ...

Mitochondrial phenotypes in purified human immune cell subtypes ...

Larger studies are required to validate and mechanistically extend these findings. These mitochondrial phenotyping data build upon established ...

Association between oxidative stress, mitochondrial function of ...

Mitochondria, as the main source of cellular energy, play an important role in maintaining the physiological function of immune cells. However, ...

Mitochondrial Function in Peripheral Blood Mononuclear Cells ...

Mitochondrial respiratory chain complexes activities using different substrates and reactive oxygen species (ROS) production were determined in both groups by ...

Influence of Immune Cell Subtypes on Mitochondrial... - Shock

Peripheral blood mononuclear cells (PBMCs) are commonly used to compare mitochondrial function in patients with versus without sepsis, but how these ...

(PDF) Mitochondrial function in peripheral blood cells across the ...

www.nature.com/npjamd ARTICLE OPEN Mitochondrial function in peripheral blood cells across the human lifespan Johannes K. Ehinger 1,2,3,9 ✉, Emil ...

Peripheral Blood Cells From Older Adults Exhibit Sex-Associated ...

Blood-based mitochondrial bioenergetic profiling is a feasible, economical, and minimally invasive approach that can be used to examine ...

Multi-modal profiling of peripheral blood cells across the human ...

However, many centenarians delay the onset of aging-related disease suggesting the presence of elite immunity that remains highly functional at ...