Modes of Regulated Cell Death in Cancer

Modes of Regulated Cell Death in Cancer - PubMed

Cell suicide pathways, termed regulated cell death (RCD), play a critical role in organismal development, homeostasis, and pathogenesis.

Modes of Regulated Cell Death in Cancer - AACR Journals

Here, we provide an overview of key RCD modalities, namely apoptosis, entosis, necroptosis, pyroptosis, and ferroptosis.

Regulated cell death (RCD) in cancer: key pathways and targeted ...

Apoptosis and autophagy are the central mechanisms that maintain cellular homeostasis and regulate cell fate. Meanwhile, there is a certain ...

Regulated cell death in cancer: from pathogenesis to treatment - PMC

Regulated cell death (RCD), including apoptosis, pyroptosis, necroptosis, and ferroptosis, is regulated by a series of evolutionarily ...

Targeting cell death pathways for cancer therapy

The Nomenclature of Cell Death Committee has developed guidelines to divide cell death modes into accidental cell death and regulated cell death ...

Regulated cell death pathways and their roles in homeostasis ...

Pyroptosis, apoptosis, necroptosis, and ferroptosis, which are the most well-studied regulated cell death (RCD) pathways, contribute to the clearance of ...

Targeting regulated cell death pathways in cancers for ... - Frontiers

RCD encompasses several mechanisms, including apoptosis, necroptosis, autophagy and the newly identified pathways of pyroptosis, ferroptosis, cuproptosis, and ...

Challenges of Regulated Cell Death: Implications for Therapy ...

... regulated cell death modes are hallmark features of tumorigenesis, they can have divergent effects on cancer cells. Consequently, there is a growing ...

Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis ...

In contrast, regulated cell death is a highly controlled and orderly process orchestrated by a series of intracellular signaling and execution mechanisms ( ...

Multiple cell death modalities and their key features (Review)

On the other hand, some types of cell death have dual and even opposing effects on tumorigenesis. Firstly, apoptosis is involved in cancer.

The role of regulated cell death in tumorigenesis and BH3-mimetics ...

In this review, we describe the roles of the different forms of regulated cell death in the development of cancer as well as their potential therapeutic ...

Nanomedicine-mediated regulated cell death in cancer ...

In addition to immunogenic apoptosis, other forms of “regulated cell death” (RCD) have also brought novel ideas to cancer immunotherapy, such as necroptosis, ...

Application of Regulatory Cell Death in Cancer: Based on Targeted ...

For common cancers, our treatment methods are still based on conventional treatment methods, such as chemotherapy, radiotherapy, and targeted drug therapy.

Regulated Cell Death - Bio-Rad Antibodies

This engagement not only induces an inflammatory response but instigates three Regulated Cell Death pathways: apoptosis, necroptosis, and pyroptosis. Read our ...

Regulated cell death: discovery, features and implications for ...

We focus on five high-profile forms of RCD, including apoptosis, pyroptosis, autophagy-dependent cell death, necroptosis and ferroptosis.

Fundamental Mechanisms of Regulated Cell Death and Implications ...

We review in detail the basic biology of nine including death receptor-mediated apoptosis, death receptor-mediated necrosis (necroptosis), mitochondrial- ...

Regulated Cell Death - ScienceDirect.com

Over the past decade, three other forms of regulated cell death have been described and characterized—necroptosis, ferroptosis, and pyroptosis. Although sharing ...

Mechanisms of Regulated Cell Death: Current Perspectives

Cell death is regulated by multiple interconnected signaling pathways and molecular mechanisms. Regulated cell death (RCD) is implicated in fundamental ...

Modes of Regulated Cell Death in Cancer - ResearchGate

... Regulated cell death (RCD) is a vital biological process involving various mechanisms like apoptosis, necroptosis, and autophagy, which are ...

Modes of Regulated Cell Death in Cancer. - Abstract - Europe PMC

Cell suicide pathways, termed regulated cell death (RCD), play a critical role in organismal development, homeostasis, and pathogenesis.