Molecular Mechanisms of Kidney Injury and Repair

Molecular Mechanisms of Kidney Injury and Repair - PubMed

Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus emphasizing the need to better understand the ...

Molecular Mechanisms of Kidney Injury and Repair - PMC

International Journal of Molecular Sciences logo Int J Mol Sci . 2022 Jan 28;23(3):1542. doi: 10.3390/ijms23031542 Molecular Mechanisms of Kidney Injury and ...

New Insights into the Molecular Mechanisms of Kidney Injury and ...

Repeated unresolved damage after acute or chronic kidney injury leads to maladaptive repair and accelerated renal fibrosis by inducing deregulation of redox ...

Identifying Common Molecular Mechanisms in Experimental and ...

Upon injury, the kidney initiates an intrinsic repair program that can result in adaptive repair with regeneration of damaged nephrons and functional recovery ...

The Road from AKI to CKD: Molecular Mechanisms and Therapeutic ...

The process from AKI to CKD is essentially a process of cellular maladaptation [49]. Once the disease enters the chronic phase, restoring ...

Mechanisms of kidney injury and repair. - ResearchGate

54 Following an injury, the kidneys will initiate healing mechanisms, which include transforming into a dedifferentiation, adapting to stressful conditions, ...

Recent Advances in Molecular Mechanisms of Kidney Injury and ...

However, inflammatory response and incomplete or maladaptive repair of the kidney after acute injury can lead to fibrosis and chronic kidney disease. Thus, ...

[PDF] Molecular Mechanisms of Kidney Injury and Repair in Arterial ...

This review summarizes the clinical and histopathological features of hypertensive kidney injury and focusses on the interplay of distinct systemic ...

Molecular Mechanisms of Kidney Injury and Repair in Arterial ...

This review summarizes the clinical and histopathological features of hypertensive kidney injury and focusses on the interplay of distinct systemic signaling ...

Molecular Mechanisms of Kidney Injury and Repair - ResearchGate

Mechanisms contributing to AKI (tubular cell death, inflammatory cell infiltration, impaired mitochondrial function, and prolonged cell-cycle ...

Molecular Mechanisms of Kidney Injury and Repair in Arterial ... - IKMB

This review summarizes the clinical and histopathological features of hypertensive kidney injury and focusses on the interplay of distinct systemic signaling ...

Cellular and molecular mechanisms of kidney injury and regeneration

In this thesis, we aimed to study the phenotype of the scattered tubular cells (STCs), a cell population distributed throughout the proximal ...

Recent advances in molecular mechanisms of acute kidney injury in ...

The specific molecular mechanisms through which insufficient autophagy in podocytes leads to DKD are still under investigation however it was recently shown ...

Molecular Mechanisms of Kidney Injury and Repair in Arterial ...

The global burden of chronic kidney disease is rising. The etiologies, heterogeneous, and arterial hypertension, are key factors contributing to the ...

Identifying Common Molecular Mechanisms in Experimental and ...

Acute kidney injury (AKI) is a highly prevalent, heterogeneous syndrome, associated with increased short- and long-term mortality. A multitude ...

Cellular and molecular pathways of renal repair after acute kidney ...

179 Citations · Molecular Mechanisms of the Acute Kidney Injury to Chronic Kidney Disease Transition: An Updated View · Activated SOX9+ renal epithelial cells ...

The complex interplay between kidney injury and inflammation

The AKI to CKD transition is a complex process mainly facilitated by maladaptive repair mechanisms. Early biomarkers mapping out this process ...

Molecular mechanisms of renal aging - Kidney International

Renal functional recovery after an episode of acute kidney injury is significantly worse in elderly patients. This decreased regenerative potential, which is a ...

Molecular mechanisms of kidney injury and repair - Biblos-e Archivo

Unraveling the cellular and molecular mechanisms involved in kidney injury and repair, including the failure of this process, may provide ...

Molecular mechanisms of diabetic kidney disease - JCI

This reduction causes compensatory hypertrophy and increased susceptibility to kidney injury that contributes to GFR decline. This phenomenon is called “ ...