Molecular mechanism of pathogenesis of dengue virus

Molecular mechanism of pathogenesis of dengue virus: Entry and ...

Interaction with specific receptor(s) at the cell surface is one of the first events in the pathogenesis of Dengue virus. However, relatively little is known ...

Molecular Insight into Dengue Virus Pathogenesis and its ...

Additionally, DENV infection activates the DNA sensor cGAS and STING pathway via unknown mechanisms. These cell-intrinsic host defense systems stimulate the ...

Dengue virus pathogenesis and host molecular machineries

During dengue infection, the virus interacts with the host cellular machinery responsible for 5' capping. DENV employs multiple strategies to ...

Molecular mechanisms in the pathogenesis of dengue infections

Dengue NS1 antigen, cytokines such as IL-1β, TNF-α, and IL-6, lipid mediators such as platelet-activating factor (PAF), leukotrienes and prostaglandins, VEGF, ...

Molecular mechanism of pathogenesis of dengue virus

However, relatively little is known about these receptors. Cellular receptors in human monocytes and mouse neural cells are main target for the viral infection.

Dengue Virus Pathogenesis: an Integrated View - ASM Journals

More than 50 years of research on dengue has resulted in a host of literature, which strongly suggests that the pathogenesis of DHF and DSS ...

Dengue virus infection: Pathogenesis - UpToDate

Binding of dengue virions to cells, which is mediated by the major viral envelope (E) glycoprotein, is critical for infectivity. The ...

Dengue virus: pathogenesis and potential for small molecule inhibitors

During the initial viral infection in dengue, the virus spreads quickly across the host's circulatory system, resulting in systemic dissemination. This phase is ...

Dengue virus infection – a review of pathogenesis, vaccines ...

Along the secretion pathway within the trans-Golgi network (TGN), the maturation of DENV requires the cleavage of pre-membrane/membrane (prM/M) ...

Molecular mechanisms in the pathogenesis of dengue infections

Bleeding following dengue virus infection occurs due to multiple mechanisms in- cluding platelet activation by NS1, seroto- nin, and PAF, accompanied by a wide.

Recent Insights Into the Molecular Mechanism of Toll-Like Receptor ...

Increased TLR3 and TLR9 expression was found in DCs of patients with dengue fever (DF) early in infection, and poor stimulation of TLR3 and TLR9 was observed in ...

Current Understanding of the Pathogenesis of Dengue Virus Infection

Dengue NS1 causes complement activation which is a host defense mechanism against the infection. It helps in opsonization of viral particles.

Dengue Virus: Molecular Biology and Recent Developments in ...

Several host and viral factors play roles in dengue pathogenesis, including variation of the DENV genome, subgenomic RNA, NS1 viral antigen, ...

Immune-Mediated Pathogenesis in Dengue Virus Infection - MDPI

Since viral entry into these cells remains unchanged, the internalized DENV particles remain unrecognized by the endogenous interferon pathway, ...

Production, Transmission, Pathogenesis, and Control of Dengue ...

aegypti, the immune deficiency (IMD) pathway shows a significant role to resist DENV susceptibility, while the increase in viral replication [35] ...

Dengue virus: epidemiology, biology, and disease aetiology

DENV non-structural proteins interfere with host antiviral responses via different mechanisms. Viral NS5 protein forms 2′-O-methylation on the 5′-cap structure ...

Molecular Mechanisms of Antiviral Agents against Dengue Virus

This review discusses the mechanisms of action employed by various antiviral agents against DENV.

Pathogenesis of Dengue: Challenges to Molecular Biology - Science

Dengue viruses replicate in cells of mononuclear phagocyte lineage, and subneutralizing concentrations of dengue antibody enhance dengue virus ...

Molecular mechanism of pathogenesis of Dengue virus: Entry and ...

Interaction with specific receptor(s) at the cell surface is one of the first events in the pathogenesis of Dengue virus. However, relatively little is known ...

Molecular mechanism of pathogenesis of dengue virus - OUCI

Wei, H.Y., Jiang, L.F., Fang, D.Y. and Guo, H.Y. (2003) Dengue virus type 2 infects human endothelial cells through binding of the viral env glycoprotein to ...