Monocytes control natural killer cell differentiation to effector ...

These data reveal a novel, unrecognized role for Txb21 expression in monocytes in promoting NK-cell development and help appreciate how various NK-cell subsets ...

Monocytes control natural killer cell differentiation to ... - PubMed

Monocytes control natural killer cell differentiation to effector ... Blood. 2011 Apr 28;117(17):4511-8. doi: 10.1182/blood-2010-10-312264. Epub 2011 Mar 9.

These data reveal a novel, unrecognized role for Txb21 expression in monocytes in promoting NK-cell development and help appreciate how various NK-cell subsets ...

Monocytes control natural killer cell differentiation to effector ...

Furthermore, in vivo depletion of myeloid cells and in vitro coculture experiments demonstrate that spleen monocytes mediate the terminal ...

(PDF) Monocytes control natural killer cell differentiation to effector ...

Furthermore, in vivo depletion of myeloid cells and in vitro coculture experiments demonstrate that spleen monocytes mediate the terminal differentiation of ...

Monocytes control natural killer cell differentiation to effector ...

NK cells are the major lymphocyte subset of the innate immune system that mediates antiviral and anti-tumor responses. It is well established that they develop ...

MICA-expressing monocytes enhance natural killer cell Fc receptor ...

It was hypothesized that NK cell effector functions against Ab-coated tumor cells were enhanced via binding of MICA on monocytes to NK cell NKG2D receptors.

Monocytes control natural killer cell differentiation to effector ... - OUCI

Abstract Natural killer (NK) cells play a major role in immunologic surveillance of cancer. Whether NK-cell subsets have specific roles during antitumor ...

NK Cells, Monocytes and Macrophages in HIV-1 Control - Frontiers

Upon pathogen recognition, monocytes and macrophages release soluble factors and express ligands that activate NK cells and boost their effector function (72).

Monocytes control natural killer cell differentiation to effector ...

Furthermore, in vivo depletion of myeloid cells and in vitro coculture experiments demonstrate that spleen monocytes mediate the terminal ...

Monocytes control natural killer cell differentiation to effector ...

Monocytes control natural killer cell differentiation to effector phenotypes · King's College London · Univ Nice Sophia Antipolis, Inserm U634 · Free Univ Med Ctr, ...

Patrolling Monocytes Control NK Cell Expression of Activating and ...

In cancer, monocytes both enhance (1, 2, 5) and inhibit (3, 4) NK cell antitumor immunity. Classical, inflammatory monocytes (CD14+CD16− in humans and Ly6C+CCR2 ...

Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory ...

Ly6Chi monocytes in particular can perform multiple roles upon tissue recruitment, and the differentiation and effector function of these cells ...

Bone marrow monocytes sustain NK cell-poiesis during non ...

This cellular dialogue leads to increased survival and maturation of NK precursors that are recruited to the liver, where they dampen the inflammatory monocyte ...

Functions of natural killer cells | Nature Immunology

Natural killer (NK) cells are effector lymphocytes of the innate immune system that control several types of tumors and microbial infections.

Recognition and Regulation of T Cells by NK Cells - Frontiers

Naive T cells (gray) are primed by DCs, expand, and differentiate into effector T cells (purple), contract and form memory T cells (red). Activation of NK cells ...

Neutrophil depletion impairs natural killer cell maturation, function ...

Interactions between NK cells and monocytes or macrophages have also been shown to be required for correct NK cell activation (Dalbeth et al., ...

Inflammatory Monocytes Activate Memory CD8+ T and Innate NK ...

Thus, inflammatory monocyte-derived IL-18 and IL-15 are critical to initiate memory CD8+ T and NK lymphocytes differentiation into antimicrobial ...

Cytokine-Induced Memory-Like Differentiation Enhances ...

Cytokine-induced memory-like natural killer (NK) cells differentiate after short-term preactivation with IL-12, IL-15, and IL-18 and display enhanced ...

Intratumoral natural killer cells show reduced effector and cytolytic ...

Depletion of NK cells led to decrease peripheral as well as intratumoral effector CD4+T-bet+ cells (Th1), and increased tumor growth. Furthermore, purified NK ...