Morphine alters respiratory control but not other key obstructive ...

Accidental opioid-related deaths are increasing. These often occur during sleep. Opioids such as morphine may worsen obstructive sleep ...

These often occur during sleep. Opioids such as morphine may worsen obstructive sleep apnoea (OSA). Thus, people with OSA may be at greater risk of harm from ...

Morphine alters respiratory control but not other key OSA phenotypes

These often occur during sleep. Opioids such as morphine may worsen obstructive sleep apnoea (OSA). Thus, people with OSA may be at greater risk of harm from ...

Opioids and obstructive sleep apnea

Opioids affect control of breathing and impair upper airway function, causing central apneas, upper airway obstruction, and hypoxemia during sleep.

Morphine alters respiratory control but not other key obstructive ...

Morphine alters respiratory control but not other key obstructive sleep apnoea ... activity, airway collapsibility or alter arousal threshold, but breathing ...

The respiratory patterns associated with opioids are ... DJ. Morphine alters respiratory control but not other key obstructive sleep apnoea ...

Effects of morphine on respiratory load detection, load magnitude ...

Pharyngeal and respiratory sensation is impaired in obstructive sleep apnea (OSA). Opioids may further diminish respiratory sensation.

Pathogenesis of sleep-disordered breathing in the setting of opioid ...

Respiratory rate was lower with opioids but rate was not ... DJ. Morphine alters respiratory control but not other key obstructive sleep apnoea phenotypes: a ...

Opioids and obstructive sleep apnea - PMC - PubMed Central

Opioids affect control of breathing and impair upper airway function, causing central apneas, upper airway obstruction, and hypoxemia during sleep.

Opioid Use Disorder, Sleep Deficiency, and Ventilatory Control

Morphine alters respiratory control but not other key obstructive sleep apnoea phenotypes: a randomised trial. Eur Respir J 2020;55:1901344 ...

Clinical implications of opioid-induced ventilatory impairment

The key respiratory control sites affected by opioids ... Morphine alters respiratory control but not other key obstructive sleep apnoea phenotypes: a randomised ...

Antagonism of morphine-induced central respiratory depression by ...

Morphine increased the phrenic nerve apnea threshold but this was antagonized by donepezil. These findings indicate that systemically administered donepezil ...

Opioids and the control of respiration - ScienceDirect.com

The degree of respiratory depression varies between drugs, but there are currently no opioids available that are devoid of respiratory side-effects. Although ...

Morphine Sulfate (Biomed) 1 mg/mL Solution for injection - Medsafe

The dosages and time intervals are preset into a microprocessor-controlled infusion pump. When the patient experiences pain, a button is depressed by the ...

Fentanyl and Morphine, but not Remifentanil, Inhibit Acetylcholine ...

Discussion · Morphine Depresses ACh at Pontine Cholinergic Cell Bodies (LDT) and Cholinergic Terminals (mPRF) · Morphine Differentially Alters Supraspinal and ...

Morphine Sulfate injection label - accessdata.fda.gov

In common with other opioids, morphine causes respiratory depression, in ... Effects of the Cardiovascular System. In therapeutic doses, morphine does not usually ...

Pathophysiological mechanisms and therapeutic approaches in ...

Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in which the airways narrow or collapse during sleep, causing obstructive sleep ...

Martins, Morphine alters respiratory control but not other key obstructive sleep apnoea phenotypes: a randomised trial, Eur Respir J., № 55, с. 1901344

Central sleep apnea - Symptoms and causes - Mayo Clinic

... control breathing. This condition is different from obstructive sleep apnea, in which breathing stops because the throat muscles relax and ...

Frontiers | Opioids, sleep, analgesia and respiratory depression

Opioids provide analgesia, as well as modulate sleep and respiration, all by possibly acting on the μ-opioid receptors (MOR). MOR's are ...