- Most partial domains in proteins are alignment and annotation artifacts🔍
- Partial protein domains🔍
- Most protein domains exist as variants with distinct functions across ...🔍
- Fritz Sedlazeck on X🔍
- Longer alignments with extended partial domains. Two proteins...🔍
- Exhaustive Enumeration of Protein Domain Families🔍
- Multiple sequence alignment of proteins with varying sizes🔍
- Jason "boundless delight " Williams on X🔍
Most partial domains in proteins are alignment and annotation ...
Most partial domains in proteins are alignment and annotation artifacts
Protein domains are commonly used to assess the functional roles and evolutionary relationships of proteins and protein families.
Most partial domains in proteins are alignment and annotation artifacts
Partial domains are largely the result of alignment and annotation artifacts and should be viewed with caution. The presence of partial ...
Most partial domains in proteins are alignment and annotation artifacts
The presence of partial domain annotations in proteins should raise the concern that the prediction of the protein's gene may be incomplete. In ...
Most partial domains in proteins are alignment and annotation artifacts
Mentioning: 30 - BackgroundProtein domains are commonly used to assess the functional roles and evolutionary relationships of proteins and protein families.
Partial protein domains: evolutionary insights and bioinformatics ...
In many other cases, there is strong evidence that this partial alignment is the result of errors in the identification of the protein sequence ...
Most partial domains in proteins are alignment and annotation artifacts
Russell DW, Schneider WJ, Yamamoto T, Luskey L, Brown MS, Goldstein JL. Domain map of the LDL receptor: sequence homology with the epidermal growth factor ...
Most protein domains exist as variants with distinct functions across ...
Accordingly, domain isotypes, compared to each other, modulate or abolish the functionality of protein domains. These results challenge the current view of ...
Fritz Sedlazeck on X: "RT @JasonWilliamsNY: Most partial domains ...
RT @JasonWilliamsNY: Most partial domains in proteins are alignment and annotation artifacts https://t.co/qVZKYTe9d3 #genomebiology.
Longer alignments with extended partial domains. Two proteins...
Searches with those extended sequences show that most of them produce long alignments; thus, those domain annotations are partial because of the inability of ...
DOGMA: a web server for proteome and transcriptome quality ...
D.A.. ,. Pearson. W.R.. Most partial domains in proteins are alignment and annotation artifacts . Genome Biol. 2015.
Exhaustive Enumeration of Protein Domain Families - ScienceDirect
We use alignments derived from an all-on-all sequence comparison to define domains within protein sequences based on a global maximum likelihood model. In all, ...
Multiple sequence alignment of proteins with varying sizes - Reddit
I searched NCBI IPG and got the proteins in a fasta file. Now using clustal omega on it I found that most of the proteins are too similar and ...
Jason "boundless delight " Williams on X: "Most partial domains in ...
Most partial domains in proteins are alignment and annotation artifacts https://t.co/qVZKYTe9d3 #genomebiology.
Most partial domains in proteins are alignment and annotation ...
Most partial domains in proteins are alignment and annotation artifacts.在哪里下载？这篇文献在哪里可以阅读？BACKGROUND:Protein domains are commonly used to ...
View Protein Domain Annotation On Multiple Alignment? - Biostars
... very basic step for people that look on protein sequences: Get the protein domains and show the alignent. Do I really have to run Hmmer ...
Pfam domain search - CLC Manuals - clcsupport.com
Annotating sequences based on pairwise alignment methods by simply transferring annotation from a known protein to the unknown partner does not take domain ...
Class 2 Slides: Functional Annotation — BICH464
Many proteins are organized into functional domains, each of which contributes to the protein's function. Domains can be reshuffled to form proteins with new ...
Dubious Pfam Domain Annotation Of A Protein - Biostars
It turns out that two related domains have significant E-value <1e-10 and they overlap with each other. One domain is common in bacteria and the ...
I believe phmmer is superior in many respects to BLASTP, and jackhmmer to PSI-BLAST. Automated annotation of protein domains. ... ing where the domain's alignment ...
20 years of the SMART protein domain annotation resource
Other, more exhaustive databases, like Pfam (13), already annotated many of these domains, but SMART's own manual annotation pipeline leads to partially ...