Multi|omics analysis identifies CpGs near G6PC2 mediating the ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Our analysis results suggest that rs2232326 and rs2232328 in G6PC2 may affect DNA methylation at CpGs near the gene and that the methylation ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

This is the first study to report CpGs near G6PC2, an important gene for regulating insulin secretion, mediating the effects of GWAS-significant SNPs on ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Aims/hypothesis An elevated fasting glucose level in non-diabetic individuals is a key predictor of type 2 diabetes. Genome-wide association studies (GWAS) ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Chung RH 1 ,. Chiu YF 1 ,. Wang WC ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

The MR analysis identified seven CpGs near the G6PC2 gene that mediated the effects of a significant SNP (rs2232326) in the gene on fasting glucose. The MR ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Request PDF | Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose | Aims/hypothesis ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose · Ren-Hua Chung · Yen-Feng Chiu · Wen-Chang Wang · Chii ...

Publication: Multi-omics analysis identifies CpGs near G6PC2 ...

The NHGRI-EBI GWAS Catalog: a curated collection of all published genome-wide association studies, produced by a collaboration between EMBL-EBI and NHGRI.

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Ren Hua Chung, Yen Feng Chiu, Wen Chang Wang ...

G6PC2 glucose-6-phosphatase catalytic subunit 2 [ (human)] - NCBI

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Haplotypes of the genes (GCK ...

GWAS Catalog - EMBL-EBI

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Chung RH et al. 2021 Diabetologia PMID ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. verfasst von: Ren-Hua Chung, Yen-Feng Chiu, Wen ...

G6PC2 gene-based association with FG levels using SKAT and ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Article. Full-text available. Jul 2021 ...

Human Genome Epidemiology Literature Finder|Home|PHGKB - CDC

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. GWAS Catalog Diabetologia 2021 ...

Longitudinal Association of DNA Methylation With Type 2 Diabetes ...

17. Chung. RH. ,. Chiu. YF. ,. Wang. WC. , et al. Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on ...

Citations to Variations in the G6PC2/ABCB11 genomic region ... - JCI

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Chung RH, Chiu YF, Wang WC, Hwu CM, Hung YJ ...

Novel insights into the genetic architecture of pregnancy glycemic ...

4. Chung, R.H. ∙ Chiu, Y.F. ∙ Wang, W.C. ... Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on ...

G 6 PC 2 A Negative Regulator of Basal Glucose-Stimulated Insulin ...

Data suggest that G6pc2 represents a novel, negative regulator of basal GSIS that acts by hydrolyzing glucose6-phosphate, thereby reducing glycolytic flux, ...

Glucose-6-phosphatase catalytic subunit 2 negatively regulates ...

43. Chung, R.H. ∙ Chiu, Y.F. ∙ Wang, W.C. ... Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on ...

Volume 64, Issue 7 | Diabetologia

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Ren-Hua Chung; Yen-Feng Chiu; Chao A. Hsiung.