Multiethnic Genetic Association Studies Improve

Multiethnic genetic association studies improve power for locus ...

To date, genome-wide association studies have focused almost exclusively on populations of European ancestry. These studies continue with ...

Multiethnic Genetic Association Studies Improve - ProQuest

Multiethnic Genetic Association Studies Improve Power for Locus Discovery. Pulit, Sara L; Voight, Benjamin F; Paul I W de Bakker. PLoS One; San Francisco Vol ...

Multi-ancestry genome-wide association analyses improve ... - Nature

We undertook phenome-wide association studies for selected associated variants as well as trait and pathway-specific genetic risk scores to ...

Trans-ethnic genome-wide association studies: advantages and ...

... genetic association studies of heterogeneous traits. ... Pulit SL, Voight BF, de Bakker PIW: Multiethnic genetic association studies improve power ...

Genome-wide Association Studies in Ancestrally Diverse Populations

Multiethnic polygenic risk scores improve risk ... The use of racial, ethnic, and ancestral categories in human genetics research.

Study of multiethnic genomes identifies 27 genetic variants ...

... ethnic groups in research studies. This paper gives us a glimpse of ... Reference. Genetic analyses of diverse populations improves discovery for ...

Imputation-Aware Tag SNP Selection To Improve Power for Large ...

... Improve Power for Large-Scale, Multi-ethnic Association Studies. Genevieve L Wojcik ,. Genevieve L Wojcik. Department of Genetics. , Stanford University School ...

Diverse study populations drive new genetic insight

The inclusion of multi-ethnic study participants in genome-wide association studies leads to new discoveries of genetic risk factors and may ...

Best practices for multi-ancestry, meta-analytic transcriptome-wide ...

Transcriptome-wide association studies (TWASs) boost detection power for and provide biological context to genetic associations by integrating ...

Multi-ethnic genome-wide association analyses of white blood cell ...

... for continued efforts in improving inclusion of racially/ethnically diverse populations in genetic association studies for complex traits.

Genome-wide association studies | Nature Reviews Methods Primers

Within-sibship GWAS improve estimates of direct genetic effects. ... Multiethnic polygenic risk scores improve risk prediction in diverse ...

Multi-Ethnic Genome-Wide Association Study of Decomposed ...

Genetic susceptibility underlies a majority of common diseases and traits, as demonstrated by genome-wide association studies (GWAS) that have ...

Multiethnic GWAS Reveals Polygenic Architecture of Earlobe ...

1 near PAX9 did not show evidence of genetic association in previous studies. ... ∙ Marchini, J. Improved whole-chromosome phasing for disease and population ...

Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in ...

We consider the utility of race and/or ethnicity categories in genome-wide association studies (GWASs) of multi-ethnic cohorts.

Genome-wide association studies: implications for multiethnic samples

... gene and linkage studies, with a substantial increase in complexity. Initial efforts to map causal effects will have to take account of ...

Challenges in conducting genome-wide association studies in ...

Challenges in conducting genome-wide association studies in highly admixed multi-ethnic ... Multiethnic genetic association studies improve power ...

Importance of human demographic history knowledge in genetic ...

We emphasise that careful consideration of the sampled populations from national and within-continental cohorts in large multi-ethnic genetic research efforts ...

Methods to maximize the utility of common fund functional genomic ...

Transcriptome-wide association study (TWAS) was proposed to link regulatory variants to target genes. ... multi-ethnic genetic studies. These proposed methods, if ...

Imputation aware tag SNP selection to improve power for multi ...

Imputation aware tag SNP selection to improve power for multi-ethnic association studies ... genetic association studies within diverse ...

(PDF) Challenges in conducting genome-wide association studies ...

In this paper, we describe the methodological steps surrounding genetic data generation, quality control, study design and analytical procedures ...