Multiplexed digital spatial profiling of invasive breast tumors from ...

The NanoString GeoMx digital spatial profiling is a new multiplexed platform that quantifies the abundance of tumor- and immune-related proteins in a ...

Recent work shows CAR‐Ts that target B7‐H3 in solid tumors can control tumor growth, both in vitro and in mouse models [37]. A separate report ...

Multiplexed digital spatial profiling of invasive breast tumors from ...

The NanoString GeoMx digital spatial profiling is a new multiplexed platform that quantifies the abundance of tumor- and immune-related ...

Multiplex Digital Spatial Profiling in Breast Cancer Research - MDPI

These approaches can be used to support pathologists in clinical decision-making by enhancing the differentiation of ductal carcinoma in situ from invasive ...

(PDF) Multiplexed digital spatial profiling of invasive breast tumors ...

killing both cancer cells and tumor vasculature [36]. Importantly, B7-H3 occurs in both the tumor and. stromal ...

Multiplexed digital spatial profiling of invasive breast tumors from ...

DSP is an efficient tool for screening tumor‐ and immune‐related markers in a simultaneous fashion and yields results that are concordant ...

Multiplex Digital Spatial Profiling in Breast Cancer Research - MDPI

Multiplex Digital Spatial Profiling in Breast Cancer Research: State-of-the-Art Technologies and Applications across the Translational Science Spectrum. Cancers ...

Multiplex Digital Spatial Profiling in Breast Cancer Research

In: Cancers, Vol. 16, No. 9, 1615, 05.2024. ... Rossi, Matilde ; Radisky, Derek C. / Multiplex Digital Spatial Profiling in Breast Cancer Research : State-of-the- ...

Spatial molecular profiling of mixed invasive ductal and ... - PNAS

Importantly, this current WHO definition of mixed invasive breast cancers MDLC differs considerably from its previous definition, i.e., tumors presenting with ...

(PDF) Multiplex Digital Spatial Profiling in Breast Cancer Research

ArticlePDF AvailableLiterature Review. Multiplex Digital Spatial Profiling in Breast Cancer ... ductal carcinoma in situ from invasive ... Tumors ...

Digital spatial profiling of the microenvironment of muscle invasive ...

Studies of DSP in other cancers revealed novel insights into the tumour microenvironment to improve risk stratification and identify ...

Spatial profiling technologies illuminate the tumor microenvironment

Similarly, breast cancer tumors show enrichment of myofibroblasts at the tumor-stroma border and depletion of lymphoid cells. In TNBC, the tumor ...

Highly Multiplexed Digital Spatial Profiling of the Tumor ... - Frontiers

Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients · Background: Immune checkpoint ...

Spatial oncology: Translating contextual biology to the clinic

Bulk and ensemble-based methods of tumor profiling have become a stalwart of the pathological workup of many tumors but are inherently limited ...

Distinct spatial immune microlandscapes are independently ... - Nature

Best practices for spatial profiling for breast cancer research with the GeoMx((R)) Digital Spatial Profiler. Cancers 13, 4456 (2021).

Multiplex Digital Spatial Profiling in Breast Cancer Research - OUCI

Dissecting Tumor-Immune Microenvironment in Breast Cancer at a Spatial and Multiplex Resolution. Cancers, 14. https://doi.org/10.3390/cancers14081999; Craig, A ...

The NanoString GeoMx® Digital Spatial Profiler - Frontiers

Multiplexed Digital Spatial Profiling of Invasive Breast Tumors From Black and White Women. Mol Oncol (2022) 16(1):54–68. doi: 10.1002/1878-0261.13017.

Protein Profiling of Breast Cancer for Treatment Decision-Making

Multiplexed digital spatial profiling of invasive breast tumors from Black and White women. ... digital spatial profiler. Cancers (Basel) ...

Spatial molecular profiling of mixed invasive ductal-lobular breast ...

... invasive ductal and lobular carcinoma, mDLC, digital spatial profiling, DSP, ... ductal and lobular tumor regions, we performed multiplexed ...

Best Practices for Spatial Profiling for Breast Cancer Research with ...

In this study, GeoMx DSP was used to profile tumor- and immune-related proteins in FFPE TMA tissue sections of invasive breast tumors from black and white women ...