NKT Cells Join the Two Step for Inflammasome ...

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β ...

The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, ...

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β ...

Inflammasome-dependent and -independent IL-1β maturation and secretion require two signals. Signal 1 is shared by both mechanisms, which involves microbe ...

NKT Cells Join the Two Step for Inflammasome-Independent IL-1b ...

Cell Reports. Preview. NKT Cells Join the Two Step for Inflammasome-Independent IL-1b Release. Jelena S. Bezbradica1,* and Sebastian Joyce2,3 ...

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β ...

The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often ...

(PDF) NKT cells join the two step for inflammasome-independent IL ...

CD1d molecules restrict the specificity and functions of Natural killer T (NKT) cells. NKT cells recognise self‐ and nonself‐lipid ligands.

NKT cells join the two step for inflammasome-independent IL-1β ...

The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, ...

NKT cells promote both type 1 and type 2 inflammatory responses in ...

Natural killer T (NKT) cells can be activated to rapidly secrete cytokines and chemokines associated with both type 1 and type 2 inflammatory responses.

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β ...

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release · About this Attention Score · Mentioned by · Citations · Readers on.

VUMC Molecular Pathogenesis on X: "Sebastian Joyce, PhD ...

... month! "NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release" Check it out ▶▶ https://t.co/8hBYfHr9Jt #MPpublications.

Type I NKT‐cell‐mediated TNF‐α is a positive regulator of NLRP3 ...

Importantly, NKT cells were found to act as regulators of NLRP3 inflammasome signaling, as NKT-cell-derived TNF-α was required for optimal IL-1β ...

Type 1 invariant natural killer T cells in chronic inflammation and ...

NKT cells have diverse functions bridging adaptive and innate immune responses. NKT cells are comprised of two main subsets, iNKT cells and type 2 NKT cells ( ...

NKT Cells Join the Two Step for Inflammasome ... - Altmetric

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release. Published in. Cell Reports, April 2020. DOI, 10.1016/j.celrep.2020.03.045. Pubmed ID.

Two-Cell Model for Inflammasome-Independent IL-1b Release...

Two-Cell Model for Inflammasome-Independent IL-1b Release Inflammasome-dependent and -independent IL-1b maturation and secretion require two signals.

Review The inflammasome: Learning from bacterial evasion strategies

Cited by (51) · FXR/TGR5 mediates inflammasome activation and host resistance to bacterial infection · A Two-Cell Model for IL-1β Release Mediated by Death- ...

Martin Duenas on X: "NKT Cells Join the Two Step for ...

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release: the invariant natural killer T cell (iNKT cell), becomes activated ...

Human Invariant NKT Cells Induce IL-1β Secretion by Peripheral ...

Similar to IL-1β production induced by TLR stimulation, the iNKT-induced pathway appeared to entail a two-step process involving NF-κB signaling and IL1B gene ...

NKT cell subsets as key participants in liver physiology and pathology

The enrichment and constitutive activation of NKT cells in the liver sinusoids indicate that these cells participate in the mechanisms that ...

Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis

Activation of the NLRP3 inflammasome requires two steps. First, extracellular stimuli prime cells, e.g., LPS binds to TLR4 to activate NF-κB and subsequent ...

Intratumoral NKT cell accumulation promotes antitumor immunity in ...

At the molecular level, NKT cells promote the production of type I IFN through the interaction of their CD40L with CD40 on myeloid cells. To evaluate the ...

Human Invariant NKT Cells Induce IL-1β Secretion by ... - Mendeley

Similar to IL-1β production induced by TLR stimulation, the iNKT-induced pathway appeared to entail a two-step process involving NF-κB signaling and IL1B gene ...