NLRP3 Inflammasome
The NLRP3 inflammasome: molecular activation and regulation to ...
NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) is an intracellular sensor that detects a broad range of microbial motifs, ...
The NLRP3 inflammasome: contributions to inflammation-related ...
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates innate immune responses by activating caspase-1 and ...
The NLRP3 Inflammasome: An Overview of Mechanisms of ...
The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion of ...
The NLRP3 Inflammasome Pathway: A Review of Mechanisms and ...
Upon activation by PAMPs and DAMPs, NLRP3 oligomerizes and activates caspase-1 which initiates the processing and release of pro-inflammatory cytokines IL-1β ...
How location and cellular signaling combine to activate the NLRP3 ...
The most well-characterized cell stress-responsive inflammasome is the NLRP3 inflammasome, which consists of a pyrin domain (PYD), a NACHT ...
The NLRP3 Inflammasome Pathway: A Review of Mechanisms and ...
The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating the innate immune system and inflammatory signaling ...
NLRP3 Inflammasome - an overview | ScienceDirect Topics
The NLRP3 inflammasome is a multiprotein platform for the activation of caspase-1, which in turn drives inflammation through the activation of proinflammatory ...
The NLRP3 inflammasome: activation and regulation - Cell Press
NLRP3 inflammasome is a cytoplasmic supramolecular complex that is activated in response to cellular perturbations triggered by infection and sterile injury.
Inflammasomes are cytosolic multiprotein complexes of the innate immune system responsible for the activation of inflammatory responses and cell death.
NLRP3 Inflammasome - an overview | ScienceDirect Topics
The NLRP3 inflammasome is a multiprotein platform which is activated upon cellular infection or stress. Its activation leads to caspase-1-dependent secretion of ...
Mechanism and Regulation of NLRP3 Inflammasome Activation
The NLRP3 inflammasome is an essential mediator of host immune responses through the activation of caspase-1 and interleukin 1 beta (IL-1β)/IL-18.
NLRP3 Inflammasome Activation - Promega Corporation
Promega offers several assays and technologies to monitor inflammasome activation, including quantifying target engagement of NLRP3 inflammasome NACHT ...
Structural Mechanisms of NLRP3 Inflammasome Assembly and ...
As an important sensor in the innate immune system, NLRP3 detects exogenous pathogenic invasions and endogenous cellular damage and responds ...
NLRP3-Inflammosome | What are inflammasome ? Which cells ...
This video talks about NLRP3-Inflammosome | What are inflammasome ? Which cells activate inflammasomes? For Notes, flashcards, daily quizzes ...
Role of the NLRP3 inflammasome in cancer
In this review, we summarize the current knowledge on the contribution of the NLRP3 inflammasome on potential cancer promotion and therapy.
The NLRP3 inflammasome - Reactome Pathway Database
The NLRP3 inflammasome · ATP binds to P2X7 · P2X7 forms oligomeric non-selective cation channels · P2X7 mediates loss of intracellular K+ · P2X7 mediates ...
NLRP3 inflammasome activation, metabolic danger signals, and ...
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an oligomeric complex that assembles in response to exogenous signals of ...
Post-translational control of NLRP3 inflammasome signaling
This review article will focus on the post-translational modifications affecting canonical (NLRP3) inflammasome signaling, inflammasome formation, and cell ...
Structural basis for the oligomerization-mediated regulation ... - PNAS
Aberrant activation of the NLRP3 inflammasome is associated with various inflammatory diseases (6, 7), including atherosclerosis, diabetes, ...
NLRP3 Inflammasome Mediates Immune-Stromal Interactions in ...
Our studies unravel the cellular diversity involved in IL-1β production and signaling in murine KD cardiovascular lesions and provide the rationale for ...