NOROVIRUS CAPSID AND ROTAVIRUS VP6 PROTEIN FOR USE ...

Norovirus capsid and rotavirus VP6 protein for use as a combination ...

[Translated] Norovirus capsid and rotavirus VP6 protein for use as a combination vaccine. Cite. Download. Patent. FI-122520-B. Inventor. VESIKARI TIMO (FI).

Norovirus capsid and rotavirus VP6 protein for use as combined ...

Norovirus capsid and rotavirus VP6 protein for use as combined vaccine. Cite. Download. Patent. US-8895015-B2. Inventor. VESIKARI TIMO (FI). BLAZEVIC VESNA (FI).

US20120093884A1 - Norovirus capsid and rotavirus vp6 protein for ...

Norovirus capsid and rotavirus vp6 protein for use as combined vaccine. Abstract. translated from. The present invention relates to a combined norovirus and ...

Norovirus VLPs and rotavirus VP6 protein as combined vaccine for ...

The proteins VP7 and VP4 contain neutralizing epitopes and induce protective immunity based on neutralizing antibodies (N-Ab) [11]. The major capsid protein VP6 ...

SG189398A1 - Norovirus capsid and rotavirus vp6 protein for use as ...

The present invention relates to a combined norovirus and rotavirus vaccine for prevention of norovirus and rotavirus infection and/orviral-induced ...

norovirus capsid and rotavirus vp6 protein for use as combined ...

More specifically, the invention comprises a method ofpreparing combination vaccine compositions comprising norovirus and rotavirus antigens, in ...

Full article: Rotavirus capsid VP6 protein acts as an adjuvant in vivo ...

Rotavirus (RV) and norovirus (NoV) are the 2 leading causes of acute viral gastroenteritis worldwide. We have developed a non-live NoV and RV vaccine ...

Unravelling aggregation propensity of rotavirus A VP6 expressed as ...

The inner capsid protein of rotavirus, VP6 ... Norovirus VLPs and rotavirus VP6 protein as combined vaccine for childhood gastroenteritis.

Rotavirus VP6 as an Adjuvant for Bivalent Norovirus Vaccine ... - MDPI

Rotaviruses (RVs) and noroviruses (NoVs) are major causes of childhood acute gastroenteritis. During development of a combination vaccine ...

Generation of Recombinant Rotaviruses Expressing Human ...

In countries where rotavirus vaccines are widely used, norovirus (NoV) has emerged as the major cause of acute gastroenteritis. Towards the goal ...

Production of norovirus-, rotavirus-, and enterovirus-like particles in ...

Purification and characterization of rota-VLPs. Rotavirus inner capsid protein VP6 was produced in High Five insect cells utilizing both the ...

Rotavirus Inner Capsid VP6 Acts as an Adjuvant in Formulations ...

This study explored an immunostimulatory effect of VP6 nanospheres on smaller antigens, P particles formed by protruding domain of a norovirus capsid protein.

Rotavirus capsid VP6 tubular and spherical nanostructures act as ...

A subunit protein vaccine candidate based on norovirus (NoV) virus-like particles (VLPs) and rotavirus (RV) VP6 protein against acute childhood gastroenteritis ...

Rotavirus VP6: involvement in immunogenicity, adjuvant activity ...

The highly conserved structural protein VP6 is highly immunogenic, and it can generate self-assembled nano-sized structures, including tubes and spheres (virus ...

Rotavirus VP6 Adjuvant Effect on Norovirus GII.4 Virus‐Like Particle ...

We have previously shown that rotavirus (RV) inner capsid protein VP6 has an adjuvant effect on norovirus (NoV) virus-like particle- (VLP-) ...

Immune responses elicited against rotavirus middle layer protein ...

Inner capsid VP6 protein is a highly conserved, abundant, and immunogenic RV protein, and VP6-specific mucosal antibodies, especially IgA, have been implicated ...

Generation of single-round infectious rotavirus with a mutation in the ...

Here, we aimed to develop a single-round infectious rotavirus by impairing the function of the viral intermediate capsid protein VP6.

Mucosal and systemic neutralizing antibodies to norovirus induced ...

Here, we successfully induced systemic and mucosal antibody responses against both rotavirus and norovirus following inoculation of recombinant rotaviruses ...

Rotavirus capsid VP6 protein acts as an adjuvant in vivo for ... - OUCI

Rotavirus capsid VP6 protein acts as an adjuvant in vivo for norovirus virus-like particles in a combination vaccine.

Generation of Recombinant Rotaviruses Expressing Human ...

Running Head: Rotavirus expressing norovirus capsid proteins. 12. 13. Key Words: rotavirus, reverse genetics, norovirus, vaccines, recombinant ...