Negative durotaxis

Durotaxis and negative durotaxis: where should cells go? - Nature

Durotaxis and negative durotaxis are processes in which cell migration is directed by extracellular stiffness. Durotaxis is the tendency of ...

Directed cell migration towards softer environments - PubMed

In agreement with this model, negative durotaxis is selectively disrupted and even reversed by the partial inhibition of actomyosin contractility. Conversely, ...

Positive and negative durotaxis – mechanisms and emerging concepts

Types of durotaxis. On stiffness gradients, single cells can exhibit either positive durotaxis (. View largeDownload slide. Types of durotaxis.

Durotaxis and negative durotaxis: where should cells go? - PubMed

Durotaxis and negative durotaxis are processes in which cell migration is directed by extracellular stiffness. Durotaxis is the tendency of ...

Positive, negative and controlled durotaxis - RSC Publishing

We show that positive and negative durotaxis found across cell types are explained by asymmetries in the cell adhesion dynamics.

Negative durotaxis: cell movement toward softer environments

We directly observed biased migration toward softer environments, ie 'negative durotaxis', in human glioblastoma cells.

Positive and negative durotaxis - mechanisms and emerging concepts

Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal dynamics, contractility and cell extrinsic cues.

Positive, negative and controlled durotaxis - NASA/ADS

Durotaxis is a physical process central to life, including embryogenesis, tissue regeneration, and tumor growth. This work proposes a mechanistic rationale ...

(PDF) Negative durotaxis: cell movement toward softer environments

How cells sense tissue stiffness to guide cell migration is a fundamental question in development, fibrosis and cancer. Although durotaxis—cell ...

Persistent random walks: a unified theory for durotaxis and negative ...

Some cells move preferentially toward stiff matrix (durotaxis), while some cells move preferentially toward soft matrix (negative durotaxis).

An elastic-damaging cohesive law for cell-substrate adhesion with ...

However, negative durotaxis has been shown to be related to the existence of a substrate optimal stiffness at which the cell deploys its maximum ...

YAP Activation in Promoting Negative Durotaxis and Acral ... - MDPI

Directed cell migration towards a softer environment is called negative durotaxis. The mechanism and pathological relevance of negative durotaxis in tumor ...

Mechanisms of durotaxis and negative durotaxis. a Cell migration is...

Right: the ability of cells to migrate from the stiff end to the soft end of the extracellular matrix is called negative durotaxis. b Myosin IIB is unpolarized ...

Durotaxis: Current Biology - Cell Press

... durotaxis can also be negative (i.e. towards soft regions). Such negative durotaxis occurs during the development of the Xenopus optic ...

Negative durotaxis: cell movement toward softer environments

Aleksi Isomursu, Keun-Young Park, Jay Hou, Bo Cheng, Ghaidan Shamsan, Benjamin Fuller, Jesse Kasim, M. Mohsen Mahmoodi, Tian Jian Lu, Guy M. Genin, Feng Xu, ...

Positive and negative durotaxis – mechanisms and emerging ...

Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal dynamics, contractility and cell extrinsic cues.

Positive, negative and controlled durotaxis. - Semantic Scholar

It is shown how durotaxis can be engineered to manipulate cell migration, which has important implications in biology, medicine, and bioengineering.

Volume 137 Issue 8 | Journal of Cell Science

Positive and negative durotaxis – mechanisms and emerging concepts · Mathilde Mathieu,Aleksi Isomursu,Johanna Ivaska. Summary: A discussion of how increasing ...

Reviews & Analysis | Communications Biology - Nature

Durotaxis and negative durotaxis: where should cells go? · Congcong Ji · Yuxing Huang.

An elastic-damaging cohesive law for cell-substrate adhesion with ...

An elastic-damaging cohesive law for cell-substrate adhesion with positive and negative durotaxis ... Abstract. Durotaxis of cells anchored to the extracellular ...