Nephrotoxicity of anticancer treatment

Nephrotoxicity of anticancer treatment - PubMed

Cytotoxic agents can cause nephrotoxicity by a variety of mechanisms. The most nephrotoxic chemotherapeutic drug is cisplatin, which is often ...

Nephrotoxicity in cancer treatment: An overview - PMC

This protocol results in low rates of nephrotoxicity during therapy. No risk factors for renal toxicity have been identified[139]. Figure 3.

Nephrotoxicity of anticancer treatment - Oxford Academic

Cisplatin [Cis-diamminedichloroplatinum(II)] is the most nephrotoxic chemotherapeutic drug, discovered over four decades ago. Nephrotoxicity is ...

Nephrotoxicity in cancer treatment: An update - ScienceDirect.com

Therefore, anticancer drug-induced renal toxicity is increasingly regarded as a principal factor that limits the efficacy of cancer treatments. Nephrotoxicity ...

Onconephrology: Update in Anticancer Drug-Related Nephrotoxicity

Renal function impairment and nephrotoxicity are one of the major limitations of cancer treatment. The relation that connects cancer and renal ...

Nephrotoxicity in cancer treatment: An update - ScienceDirect.com

... cancer drug-induced renal pathophysiology, resulting in quite limited and largely ineffective management of anticancer drug-induced nephrotoxicity.

Nephrotoxicity of recent anti-cancer agents | Clinical Kidney Journal

Gene polymorphisms in the renal cytochrome P450 enzyme system, which favour reduced metabolism and renal excretion, enhance nephrotoxic risk.

Global burden of anticancer drug-induced acute kidney injury and ...

While some studies have attempted to elucidate the nephrotoxicity of novel drugs, research on the long-term and large-scale effects of various ...

Anticancer Agents and Nephrotoxicity: A Mini Review

... nephrotoxic effects developed by anticancer drugs. The anticancer drug developed nephrotoxicity limits the necessary treatment of the ...

The Nephrotoxicity of Drugs Used in Causal Oncological Therapies

As a result of its accumulation in the renal tubular cells, its metabolism takes place and the formation of two nephrotoxic metabolites of ...

Management of nephrotoxicity of chemotherapy and targeted agents

Nephrotoxicity in cancer treatment: an overview. World J Clin Oncol. 2020; 11 ... Prevalence of renal insufficiency in cancer patients and implications for ...

Nephrotoxicity of chemotherapy and other cytotoxic agents - UpToDate

... nephrotoxic drugs were used in 80 percent of chemotherapy sessions [1]. The nephrotoxicity of select conventional cytotoxic chemotherapy ...

Nephrotoxicity of anticancer drugs: an underestimated problem?

Nephrotoxicity is an inherent adverse effect of certain anticancer drugs and may result in a variety of functional consequences that include any ...

NEPHROTOXICITY OF ANTICANCER DRUGS

The proliferation in recent years of novel anticancer agents has broadened the range of known anticancer thera- peutic agents that cause nephrotoxic renal ...

Nephrotoxicity Associated with Novel Anticancer Agents (Aflibercept ...

In this article, after presenting clinical cases we discuss the differing renal toxicity of three novel anticancer agents (aflibercept, dasatinib, and nivolumab) ...

Prevalence of Renal Insufficiency in cancer patients and ...

The use of potentially nephrotoxic therapies in patients who are at high risk for drug renal toxicity because of preexisting renal impairment ...

Conventional Chemotherapy Nephrotoxicity

Nephrotoxicity and Risk Factors. While carboplatin is a nephrotoxic agent, the incidence of kidney injury is considerably lower than cisplatin.

Cancer and renal insufficiency results of the BIRMA study - Nature

high risk for drug-induced nephrotoxicity. The Belgian Renal Insufficiency and Anticancer ... therapy during treatment. Our study shows ...

Nephrotoxicity in cancer treatment: An update | Request PDF

Request PDF | Nephrotoxicity in cancer treatment: An update | It has been ... anticancer drug-treated patients receive potentially nephrotoxic drugs, while the

Guidelines for treatment of renal injury during cancer chemotherapy ...

Consequently, onco-nephrology has emerged as a new clinical field concerned with the management of nephrotoxicity in cancer drug therapy, ...