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Neural Circuit Mechanisms of Fear Extinction


Neuronal circuits of fear extinction - PubMed

Fear extinction is a form of inhibitory learning that allows for the adaptive control of conditioned fear responses.

Neural circuit mechanisms of fear extinction. - APA PsycNet

As the domain of fear extinction research continues to grow, further basic and translation efforts will contribute to understanding of fear-based and ...

Neural circuits for the adaptive regulation of fear and extinction ...

Decades of work assessing the neural circuitry of fear learning point to the amygdala as a critical neural substrate of aversive learning and memory. The ...

A translational perspective on neural circuits of fear extinction

The typical fear conditioning and extinction paradigm in humans consists of pairing a picture (CS) with an aversive consequence (US). The US usually entails ...

Functional anatomy of neural circuits regulating fear and extinction

Owing to substantial progress toward understanding the neural mechanisms underlying the context specificity of fear extinction, there is now a general consensus ...

Neural Mechanisms of Extinction Learning and Retrieval - Nature

Studies on the neurobiology of extinction have been driven by the well-documented circuitry of conditioned fear. The basolateral amygdala (BLA) ...

Unrelenting Fear Under Stress: Neural Circuits and Mechanisms for ...

These data suggest that stress-induced activation of brain neuromodulatory systems biases fear memory at the expense of extinction learning. Behavioral and ...

Parsing neural circuits of fear learning and extinction across basic ...

Through the lens of neural circuits, in this article, we aim to review the current knowledge of fear learning and extinction in both animals and humans, and to ...

Central amygdala micro-circuits mediate fear extinction - Nature

Recent studies show, however, the CEA is not merely an output relay of fear responses but contains multiple neuronal subpopulations that ...

Neuronal circuits of fear extinction - Herry - 2010 - Wiley Online Library

Fear extinction is a form of inhibitory learning that allows for the adaptive control of conditioned fear responses.

Neuronal circuits of fear memory and fear extinction - De Gruyter

Extreme variation in, or perturbation of these mechanisms can lead to dispro- portional and prolonged (even irrevers- ible) emotional states, which are experi-.

UChicago researchers identify neural circuit implicated in fear ...

Together, Sheffield said, the results describe a role of NR-CA1 in fear extinction. “This pathway suppresses the fear memory in real time, which ...

Uncertainty-Dependent Extinction of Fear Memory in an Amygdala ...

Although the PREE has been explained by psychological theories, the neural mechanisms underlying the PREE remain largely unclear. Here, we developed a neural ...

Neural Circuit Mechanisms of Fear Extinction | Request PDF

The neural circuitry underlying fear conditioning and extinction is discussed in greater detail in rodent models, followed by an explanation of some of the ...

Dopamine regulation of contextual fear and associated neural circuit ...

In contrast, longer or repeated context re-exposure alone results in contextual fear extinction, which is a form of inhibitory learning that ...

Functional architecture of dopamine neurons driving fear extinction ...

During fear extinction, dopamine (DA) neurons signal the absence of the expected aversive outcome, and this extinction prediction error (EPE) ...

Neural Circuit Mechanisms of Fear Extinction | Anxiety Disorders

The neural circuitry underlying fear conditioning and extinction is discussed in greater detail in rodent models, followed by an explanation of some of the ...

Synaptic Encoding of Fear Extinction in mPFC-amygdala Circuits

These synaptic mechanisms could contribute to the encoding of extinction memory by diminishing the ability of projections from the mPFC to drive ...

Neural and cellular mechanisms of fear and extinction memory ...

Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit.

Neural circuits and mechanisms involved in Pavlovian fear ...

Pavlovian or classical fear conditioning is recognized as a model system to investigate the neurobiological mechanisms of learning and memory in the ...