Neural basis of opioid|induced respiratory depression and its rescue

Neural basis of opioid-induced respiratory depression and its rescue

Here, we report that neurons expressing the μ-opioid receptors in the lateral parabrachial nucleus of the pontine respiratory group are necessary and ...

Neural basis of opioid-induced respiratory depression and its rescue

Opioid-induced respiratory depression (OIRD) causes death following an opioid overdose, yet the neurobiological mechanisms of this process ...

Frontiers | Opioids, sleep, analgesia and respiratory depression

Neural basis of opioid-induced respiratory depression and its rescue. Proc. Natl. Acad. Sci. 118, e2022134118. doi: 10.1073/pnas.2022134118.

Dual mechanisms of opioid-induced respiratory depression in ... - eLife

The neuronal control of breathing is highly vulnerable to exogenous opioid-based analgesics and drugs of abuse. As a result, clinical and ...

Current research in pathophysiology of opioid-induced respiratory ...

Neural basis of opioid-induced respiratory depression and its rescue. Proc. Natl. Acad. Sci. USA 118: e2022134118. doi.org/10.1073/pnas.2022134118. Google ...

Neural basis of opioid-induced respiratory depression and its rescue

Chemogenetic inactivation of PBLOprm1 neurons mimics OIRD in mice, whereas their chemogenetic activation following morphine injection rescues ...

Neural basis of opioid-induced respiratory depression and its rescue

PDF | Opioid-induced respiratory depression (OIRD) causes death following an opioid overdose, yet the neurobiological mechanisms of this ...

Latent neural population dynamics underlying breathing, opioid ...

... the basis of respiratory-related ... Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding.

Opioids, sleep, analgesia and respiratory depression

Neural basis of opioid-induced respiratory depression and its rescue. Proc. Natl. Acad. Sci. 118 e2022134118. 10.1073/pnas.2022134118 [DOI] ...

Neural basis of opioid-induced respiratory depression and its rescue

Neural basis of opioid-induced respiratory depression and its rescue · Proceedings of the National Academy of Sciences of the United States of America, May 2021.

Neural basis of opioid-induced respiratory depression and its rescue

Opioid-induced respiratory depression (OIRD) causes death following an opioid overdose, yet the neurobiological mechanisms of this process are not well ...

Neuronal mechanisms underlying opioid-induced respiratory ...

... the mechanisms of opioid-induced respiratory depression. Rhythmogenetic ... rescues morphine-induced respiratory rate depression (87, 212). This occurs ...

Neural basis of opioid-induced respiratory depression and its rescue

Significance Opioid-induced respiratory depression (OIRD) is the direct cause of death from opioid overdose, which accounts for the current global opioid ...

Opioids and the control of respiration - ScienceDirect.com

The ultimate aim of combating opioid-induced respiratory depression would benefit patients in pain and potentially reduce deaths from opioid overdose. By ...

Opioid Overdose: Limitations in Naloxone Reversal of Respiratory ...

The many deaths from opioids indicate that rescue from respiratory depression is often ineffective or too late (or not initiated). Interestingly, survival after ...

What Is Opioid-Induced Respiratory Depression? - Bicycle Health

... the opioid's effects and stopping the subsequent respiratory depression that the opioid ... Neural Basis of Opioid-Induced Respiratory Depression and Its Rescue.

Your search: "author:Liu, Shijia" - eScholarship

Neural basis of opioid-induced respiratory depression and its rescue · Liu, Shijia;; Kim, Dong-Il;; Oh, Tae Gyu;; Pao, Gerald M;; Kim, Jong-Hyun;; Palmiter ...

Opioid suppression of an excitatory pontomedullary respiratory ...

(2021) Neural basis of opioid-induced respiratory depression and its rescue. PNAS 118:e2022134118. https://doi.org/10.1073/pnas.2022134118.

Opioids and the control of respiration - British Journal of Anaesthesia

The ultimate aim of combating opioid-induced respiratory depression would benefit patients in pain and potentially reduce deaths from opioid overdose. By ...

Researchers identify neurons involved in overdose deaths

... opioid-induced respiratory depression, or OIRD, the disrupted breathing that causes overdose deaths. It also shows how blocking these ...