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New Approach Methods in Immunology


New Approach Methods in Immunology | Frontiers Research Topic

Motivation to work on non-animal methods, or new approach methods (NAM), stems from economical and ethical considerations, and is supported by public pressure.

Editorial: New approach methods in immunology - PMC

proposed a novel train of thought, “integration”, to augment the breadth and depth of bioinformatics in peptide-based therapeutics. The ...

Editorial: New approach methods in immunology - PubMed

Affiliations. 1 Center for Alternatives to Animal Testing (CAAT), Doerenkamp-Zbinden-Chair for Evidence-based Toxicology, Johns Hopkins ...

Editorial: New approach methods in immunology - ResearchGate

Editorial: New approach methods in immunology ... Content may be subject to copyright. ... the need to bridge the translational gap between animal ...

Immunological techniques - Latest research and news - Nature

Related Subjects · Antibody generation · Antibody isolation and purification · ELISA · ELISPOT · Immunoblotting · Immunohistochemistry · Immunoprecipitation · Immune ...

Small molecules induce trained immunity, opening a new approach ...

A University of Chicago Pritzker School of Molecular Engineering (PME) team has found several small molecule candidates that induce this trained immunity.

Synthetic immunology: Approaching a turning point in the treatment ...

Synthetic immunology, an innovative field of research that could lead to fundamentally new approaches and methods in the treatment of infectious diseases and ...

New Approaches to Human Immunology - ScienceDirect

New methodologies and approaches have also shed light on basic immunology such as the relative importance of clonal deletion in T cell tolerance and the ...

Exploring new perspectives in immunology - Cell Press

Several conceptual pillars form the foundation of modern immunology, including the clonal selection theory, antigen receptor diversity, immune memory, and ...

New Approach Methodologies (NAMs) Within TSCA

Computational toxicology and bioinformatics · High-throughput screening methods · Testing of substances in chemical categories · Tiered testing methods · In vitro ...

New Approach Methodologies in Immunotoxicology: Challenges ...

The term “new approach methodologies” (NAMs) refer to the approaches which are not based on animal models. They are applied in hazard and risk assessment of ...

Alternatives to animal testing: New Approach Methodologies (NAMs)

Our focus to improve laboratory methods for Immunotoxicological testing is important because it focuses on understanding how exposure to various ...

Computational Methods in Immunology and Vaccinology: Design ...

The design of new biomolecules able to harness immune mechanisms for the treatment of diseases is a prime challenge for computational and ...

Journal of Immunological Methods | ScienceDirect.com by Elsevier

The Journal of Immunological Methods is devoted to covering techniques for: (1) Quantitating and detecting antibodies and/or antigens.

4 The Landscape of New Approach Methodologies

As emphasized earlier in this chapter, the usefulness of new approach methodologies extends beyond opportunities to reduce reliance on NHPs; 2D and 3D cell ...

New Approach Methods (NAMs) in the science- based derivation of ...

Lothar Rink, Uniklinik RWTH Aachen, AöR, Department of Immunology. Private lecturer Dr. rer. nat. Bernd Roßbach, University Medicine of the Johannes ...

A guide to systems-level immunomics | Nature Immunology

... approaches are creating opportunities to complement standard immunological methods with new insights into immune-system dynamics. Like ...

Systems Immunology Approaches to Metabolism - Annual Reviews

... new approaches to connecting metabolism and immunity. In this review, we discuss recent studies that highlight the complex physiological ...

New Approach Methodologies in Immunotoxicology - OUCI

Abstract: To maintain the integrity of an organism, a well-functioning immune system is essential. Immunity is dynamic, with constant surveillance needed to ...

New Approach Methods (NAMs) - FDA

New Approach Methods (NAMs) ... Researchers historically gained information about the toxicity of a substance through rodent and other animal ...