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New approaches to the systemic treatment of melanoma


New approaches to the systemic treatment of melanoma - PubMed

Metastatic melanoma is an incurable condition with a median survival of about 6 months. Chemotherapy can result in objective tumour responses but only in a ...

New approaches to the systemic treatment of melanoma

Metastatic melanoma is an incurable condition with a median survival of about 6 months. Chemotherapy can result in objective tumour responses but only in a ...

Systemic Therapy for Melanoma: ASCO Guideline Update

In the past decade, 12 new drugs have been approved for unresectable melanoma, along with four new approvals in the adjuvant setting and increasing research in ...

New approaches to the systemic treatment of melanoma

Phase II studies have suggested that combining chemotherapy with biological response modifiers may result in higher response rates, in the order of 50%.

Systemic treatment of metastatic melanoma: new approaches

The field of melanoma therapeutics has experienced a dramatic paradigm shift over the last 12 months through recent discoveries of novel therapeutics ...

Systemic treatment of metastatic melanoma: New approaches

Traditionally, therapeutic approaches to the systemic treatment of melanoma would be limited by a lack of candidates beyond chemotherapeutic ...

New Approaches to Systemic Therapy for Patients with Stage III ...

“Whether targeted therapy or PD-1-based immunotherapy, the use of adjuvant therapy after surgical resection in stage III melanoma reduces the risk of recurrence ...

New Melanoma Treatment Approaches Being Explored

One approach called 'targeted therapy' turns off the molecular switches that drive melanoma tumor growth. Currently, targeted therapies are only ...

Emerging Strategies in Systemic Therapy for the Treatment of ...

Recent years have seen clinically important advances in the treatment of melanoma with the advent of various systemic immunotherapies and targeted therapies.

A Review of Current and Pipeline Drugs for Treatment of Melanoma

Advanced melanoma cases often require a multidisciplinary approach with combination therapies or novel agents to achieve better responses. Combining different ...

Treatment Options for Melanoma Patients

Immunotherapy is a cancer treatment that stimulates the immune system to fight cancer anywhere in the body. This treatment may either be systemic, meaning that ...

Systemic treatment of metastatic melanoma with BRAF and other ...

Outline · Choice of BRAF plus MEK inhibitor therapy · Dabrafenib plus trametinib · Encorafenib plus binimetinib · Vemurafenib plus cobimetinib.

Treatment of Melanoma Skin Cancer, by Stage

If surgery is not an option, radiation therapy or systemic treatment (immunotherapy, targeted therapy, or chemo) can be used. Recurrence in ...

Melanoma biology and treatment: a review of novel regulated cell ...

The treatment of advanced melanoma, particularly metastatic cases, remains challenging with poor outcomes. Targeted therapies involving BRAF/MEK ...

Emerging Novel Therapeutic Approaches for Treatment of Advanced ...

The introduction of immune checkpoint inhibitors and targeted therapy for the treatment of unresectable advanced or metastatic melanoma has changed the ...

Systemic treatment of metastatic melanoma lacking a BRAF mutation

Outline · Benefits of immunotherapy over chemotherapy · Patients with features of aggressive disease · - Nivolumab plus ipilimumab (preferred).

Novel Approaches to the Systemic Management of Uveal Melanoma

No adjuvant systemic therapy has been shown to reduce the risk of metastasis or improve overall survival in patients with UM following treatment ...

Systemic treatment of metastatic melanoma: New approaches - Hamid

13Boasberg PD: Phase II trial of nab-paclitaxel and bevacizumab as first-line therapy in patients with unresectable melanoma. J Clin Oncol 2011; ...

Systemic treatment of metastatic melanoma: New approaches

The field of melanoma therapeutics has experienced a dramatic paradigm shift over the last 12 months through recent discoveries of novel therapeutics ...

New Approaches in the Treatment of Metastatic Melanoma

Although melanoma is a relatively chemoresistant malignancy, systemic chemotherapy remains the primary treatment for metastatic melanoma.