New insights into the function of the NLRP3 inflammasome in ...

In this review, we aim to elucidate the underlying mechanisms of the NLRP3 inflammasome and its relevance in sarcopenia of various etiologies.

Sarcopenia is one of the most common skeletal muscle disorders and is characterized by infirmity and disability.

New Insights into the Role of NLRP3 Inflammasome in ... - NCBI

The NLR family pyrin domain containing 3 (NLRP3) inflammasome activation is required in the lung inflammatory responses in the development of COPD.

New insights into the functions of inflammasomes

For diseases mediated by NLRP3, AIM2, NLRC4, and Pyrin, understanding inflammasome biology could identify therapeutic targets.

New Insights on NLRP3 Inflammasome: Mechanisms of Activation ...

The major role of NLRP3 inflammasome is after detecting endogenous and exogenous stress signals it translates them into inflammatory reactions ( ...

New Insights into Mechanisms Controlling the NLRP3 ...

Emerging genetic and pharmacological evidence suggests that NLRP3 inflammasome activation may also be involved in acute lung inflammation after viral infection ...

NLRP3 inflammasome: a key player in the pathogenesis of life-style ...

Proinflammatory cytokines and chemokines play a crucial role in regulating the inflammatory response, which is essential for the proper ...

New Insights Into the Interplay Among Autophagy, the NLRP3 ...

Inflammasome activation also has been recently recognized to play a critical role in the development of obesity-associated liver disease. The ...

Novel Insights Into the NLRP3 Inflammasome in Atherosclerosis

Accumulated evidence reveals a causative role for the NLRP3 inflammasome in the initiation and progression of atherosclerosis, although the ...

New insights into mechanisms controlling the NLRP3 inflammasome ...

Semantic Scholar extracted view of "New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease." by D. De Nardo et al.

New insights into the regulatory roles of glutathione in NLRP3 ...

When compared with activation signals of other inflammasomes, this activation signal of the NLRP3 inflammasome can be triggered by a wide range of DAMPs (e.g. ...

Mechanistic and therapeutic insights into the function of NLRP3 ...

Regulating host immune function and protecting against microbial invasion and cell damage, the NLRP3 inflammasome plays a crucial role. By ...

An update on the regulatory mechanisms of NLRP3 inflammasome ...

The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is a multiprotein complex involved in the release of mature ...

Recent insights into the regulatory networks of NLRP3 ...

Summary: The NLRP3 inflammasome is a critical mediator of inflammation subject to dense regulatory networks to prevent erroneous ...

Role of the NLRP3 inflammasome in cancer

As noted above, inflammasomes are the multi-protein platform in the innate immune system that induce procaspase-1 activation and inflammatory ...

(PDF) New Insights on NLRP3 Inflammasome: Mechanisms of ...

PDF | Inflammasomes are important modulators of inflammation. Dysregulation of inflammasomes can enhance vulnerability to conditions such as ...

The NLRP3 inflammasome: contributions to inflammation-related ...

... to new methods for targeting the NLRP3 inflammasome to treat inflammation-related diseases, and provide new ideas for clinical treatment.

New Insights into the Role of NLRP3 Inflammasome in ...

Emerging studies based on tests on samples from COPD patients, animal models, pharmacological and genetic data suggest that the NLR family pyrin ...

Interactions between NLRP3 inflammasome and glycolysis in ...

NLRP3 inflammasome plays an important role in the occurrence, development and prognosis of many chronic inflammatory diseases, such as ...

New Insights on NLRP3 Inflammasome: Mechanisms of Activation ...

Abstract Inflammasomes are important modulators of inflammation. Dysregulation of inflammasomes can enhance vulnerability to conditions such as ...