Non|Edg family LPA receptors

Non-Edg family LPA receptors: the cutting edge of LPA research

Lysophosphatidic acid (LPA) is a bioactive lipid mediator with diverse physiological and pathological actions on many types of cells. Originally, LPA was ...

Non-Edg family lysophosphatidic acid (LPA) receptors - ScienceDirect

This review article focuses on the identification, properties and possible functions of the non-Edg family LPA receptors.

Non-Edg family LPA receptors: the cutting edge of LPA research

The discovery of these novel LPA receptors now provides a new framework for understanding pleiotropic functions of LPA. Recent studies have ...

Role of lysophosphatidic acid and its receptors in health and disease

In 2003, beyond the classical Edg family LPA receptors, the first non-Edg LPA receptor, which was further called LPAR4, was identified during ...

Current progress in non-Edg family LPA receptor research

Analyses of these non-Edg family LPA receptors have begun to fill in gaps to understand biological functions of LPA such as platelet aggregation and vascular ...

Current progress in non-Edg family LPA receptor research

... LPA [10]. 3. Pharmacological characterization of LPA receptor ligands on non-Edg family LPA receptors. LPA is not a single molecular entity; there are many LPA ...

Lysophospholipid (LPA) receptors | G protein-coupled receptors

... LPA receptor 1 | Lpar1 | lysophosphatidic acid receptor Edg-2. Genes, LPAR1 ... (2011) Non-Edg family LPA receptors: the cutting edge of LPA research. J ...

LPA receptor signaling: pharmacology, physiology, and ...

The most recent addition to the LPA receptor family is LPA6. In ... Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors.

Current progress in non-Edg family LPA receptor research.

The 3.2 Å crystal structure of LPA6 is determined, to clarify the ligand recognition mechanism of the non-EDG family of Lpa receptors, and Notably, ...

Structural mechanisms of potent lysophosphatidic acid receptor 1 ...

Owing to their amino acid sequence identity, LPA1-3 belong to the endothelial differentiation gene (EDG) family along with sphingosine-1- ...

Current progress in non-Edg family LPA receptor research

There are known G-protein coupled receptors (GPCR) for lysophosphatidic acid (LPA) called the Endothelial differentiation gene (Edg) family of receptors (Takuwa ...

A growing family of receptor genes for lysophosphatidic acid (LPA ...

... receptor for LPA, along with related expression data. ... (1995) Cloning and characterization of a new member of the G-protein coupled receptor EDG family, ...

LPA 1 receptor - IUPHAR/BPS Guide to PHARMACOLOGY

... LPA receptor 1 | Lpar1 | lysophosphatidic acid receptor Edg-2 ... (2000) Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by ...

Non-Edg family LPA receptors: The cutting edge of LPA research

These 'non-Edg family' LPA receptors now provide a new framework for understanding the diverse functions of LPA, including vascular development, platelet ...

Lysophosphatidic acid (LPA) receptors of the EDG family are ...

Lysophosphatidic acid (LPA, 1- or 2-acyl-sn-glycero-3-phosphate) is a lipid mediator with diverse biological properties [1, 2]. It activates ...

Non-Edg family lysophosphatidic acid (LPA) receptors

However, even after finding of the Edg family LPA receptors, the existence of an additional LPA receptor(s) has been implied by several reports. In 2003, we ...

The Edg Family of G-Protein Coupled Receptors - Exalpha

... families and renamed according to the ligand which they bind.Activation of the Edg receptors by S1P or LPA has multiple effects on cells ...

Lysophosphatidic acid (LPA) receptors of the EDG family ... - CORE

tivity relationship of various LPA and LPA analogs using. LPA non-responding Sf9 insect cells expressing each cloned. LPA receptor by measuring intracellular ...

Non-Edg family LPA receptors: the cutting edge of LPA research

Non-Edg family LPA receptors: the cutting edge of LPA research. https://doi.org/10.1093/jb/mvr087 · Full text. Journal: Journal of Biochemistry, 2011, № 3, p ...

Current progress in non-Edg family LPA receptor research - OUCI

Choi, LPA receptors: subtypes and biological actions, Annu. · Sano, Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and ...