Noncoding RNA therapeutics for substance use disorder

Noncoding RNA therapeutics for substance use disorder - PMC - NCBI

In this review, we describe different ncRNA classes involved in SUD, provide an overview of the modalities used to manipulate ncRNAs, and highlight ncRNA-based ...

Noncoding RNA therapeutics for substance use disorder - PubMed

Although noncoding RNAs (ncRNAs) have been shown to regulate maladaptive neuroadaptations that drive compulsive drug use, ncRNA-targeting therapeutics for ...

Noncoding RNA therapeutics — challenges and potential solutions

Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), represents an attractive ...

Noncoding RNA therapeutics for substance use disorder

NcRNA processes implicated in SUD are reviewed, recent therapeutic approaches for targeting ncRNAs are discussed, and potential opportunities and challenges ...

The Emerging Role of Non-Coding RNAs in Drug Addiction - Frontiers

We conclude that ncRNAs are importantly involved in the persistent neuroadaptations associated with addiction-related behaviors.

Noncoding RNA therapeutics for substance use disorder - OUCI

Although noncoding RNAs (ncRNAs) have been shown to regulate maladaptive neuroadaptations that drive compulsive drug use, ncRNA-targeting therapeutics for ...

Noncoding RNAs in Drug and Alcohol Research - Journals

Recent Articles · Noncoding RNA therapeutics for substance use disorder · Hippocampal ceRNA networks from chronic intermittent ethanol vapor-exposed male mice and ...

Preclinical and Clinical Development of Noncoding RNA ...

In summary, a combination of novel therapeutic RNA targets, large-animal models, ex vivo studies with human cells/tissues, and new delivery ...

Epigenetic and non-coding regulation of alcohol abuse and addiction

MiRNAs are anti-sense complements to the 3′ and 5′-untranslated regions (UTRs) of gene transcripts that promote RNA degradation and/or block RNA translation, ...

Noncoding RNA therapeutics for substance use disorder. - MediFind

Although noncoding RNAs (ncRNAs) have been shown to regulate maladaptive neuroadaptations that drive compulsive drug use, ncRNA-targeting ...

A systematic review of non-coding RNA therapeutics in early clinical ...

Dysregulation of these molecules has been associated with several diseases, including cancer [10,11,12]. NcRNAs can affect cancer development by ...

Long Non-Coding RNAs: The New Frontier into Understanding the ...

Alcohol use disorder (AUD) is a complex, chronic, debilitating condition impacting millions worldwide. Genetic, environmental ...

RNA-based therapeutics: an overview and prospectus - Nature

Several RNA-based medications have been approved for clinical use, while others are still under investigation or preclinical trials. Various ...

The Emerging Role of Non-Coding RNAs in Drug Addiction

Recent evidence suggests that non-coding RNAs (ncRNAs) play an important and dynamic role in transcriptional regulation, epigenetic signaling, ...

The Emerging Role of Non-Coding RNAs in Drug Addiction

It is concluded that nc RNAs are importantly involved in the persistent neuroadaptations associated with addiction-related behaviors, and that therapies ...

REVIEW Long non-coding RNAs: From disease code to drug role

The application of lncRNAs as biomarkers or intervention targets can provide new insights into the diagnosis and treatment of diseases. This paper has focused ...

Noncoding RNAs Emerging as Drugs or Drug Targets - MDPI

As the effect of ncRNAs in various diseases has been increasingly revealed, it is possible to design novel ncRNA-based drugs for clinic use. ncRNA-based drugs, ...

Role of microRNAs in the pathophysiology of addiction - Gowen - 2021

There are both heritable and epigenetic mechanisms underlying drug addiction. Emerging evidence suggests that non-coding RNAs (ncRNAs) such as ...

RNA Therapeutics for Substance Use Disorders RNA Dünyasından ...

4. Seyednejad SA, Sartor GC. Noncoding RNA therapeutics for substance use disorder. Advances in drug and alcohol research, 2022;2:10807. https ...

Noncoding RNAs in cancer therapy resistance and targeted drug ...

MiRNA mimics and anti-miRNAs are two major therapeutic forms used to mimic the function of endogenous tumor suppressor miRNAs and to deplete ...