- Explaining the amyloid research study controversy🔍
- Notes on the Alzheimer's Disease Amyloid Beta Scandal ...🔍
- Faked Beta|Amyloid Data. What Does It Mean?🔍
- Inconsistencies and Controversies Surrounding the Amyloid ...🔍
- Blots on a field?🔍
- Alzheimer's🔍
- Alzheimer's theory undermined by accusations of fabricated research🔍
- Questions concerning the role of amyloid|β in the definition ...🔍
Notes on the Alzheimer's Disease Amyloid Beta Scandal ...
Explaining the amyloid research study controversy
Allegations have been made about a research study investigating amyloid protein build up in the brains of people living with Alzheimer's disease.
Notes on the Alzheimer's Disease Amyloid Beta Scandal ... - BrainKey
What is the theory that is taking a hit? From a very high-level, the theory states that toxic proteins clump together (beta-amyloid/toxic oligomers”) and damage ...
Faked Beta-Amyloid Data. What Does It Mean? | Science | AAAS
An association between Alzheimer's disease and amyloid protein in the brain has been around since. . .well, ever since the early 1900s, when ...
Inconsistencies and Controversies Surrounding the Amyloid ...
The amyloid hypothesis has driven drug development strategies for Alzheimer's disease for over 20 years. We review why accumulation of amyloid-beta (Aβ) ...
And in 1991, researchers traced family-linked Alzheimer's to mutations in the gene for a precursor protein from which amyloid derives. To many ...
Alzheimer's: New Study Supports Amyloid Hypothesis But Suggests ...
An analysis of human brain cells provides new evidence in support of the “amyloid hypothesis,” the prevailing idea that Alzheimer's is caused by the ...
Alzheimer's theory undermined by accusations of fabricated research
For decades, a leading theory stated that the amyloid beta protein formed sticky plaques in the brain that were the main cause of Alzheimer's.
Questions concerning the role of amyloid-β in the definition ...
The dominant hypothesis of Alzheimer's disease (AD) aetiology, the neuropathological guidelines for diagnosing AD and the majority of high-profile therapeutic ...
Alzheimer's study controversy: What does it mean for future research?
A now-seminal study published in 2006 provided evidence that the toxic accumulation of a protein called beta-amyloid in the brain was tied ...
Amyloid β-based therapy for Alzheimer's disease - Nature
Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease (AD), and its accumulation has been considered as ...
Where has Alzheimer's research gone wrong? with Karl Herrup (Ep ...
The leading theory for decades has been that abnormal amyloid plaques in the brains of those who suffer from the disease are the central cause.
What now for the amyloid hypothesis? | Drug Discovery News
But a team of sleuths found that many of the papers describing Aβ*56 were fraudulent and contained an array of faked images and blots. The fraud ...
A specific amyloid-β protein assembly in the brain impairs memory
We propose that Aβ*56 impairs memory independently of plaques or neuronal loss, and may contribute to cognitive deficits associated with Alzheimer's disease.
Amyloid Beta - an overview | ScienceDirect Topics
Dysfunction of the proteins that regulate amyloid plaque degradation, transport, and internalization can also cause Alzheimer's disease. Outcome. A key aspect ...
Monoclonal Antibodies Directed Against Amyloid for the Treatment ...
The role of amyloid in Alzheimer's disease remains complicated for at least three reasons. First, amyloid plaques are seen in other diseases, such as dementia ...
A comparison between tau and amyloid-beta cerebrospinal fluid ... ” An Analysis of questions raised following amyloid. PET results ...
Failure to demonstrate efficacy of aducanumab: An analysis of the ...
Aducanumab's efficacy as a treatment for the cognitive dysfunction in Alzheimer's disease cannot be proven by clinical trials with divergent outcomes.
The performance of plasma amyloid beta measurements in ...
The extracellular buildup of amyloid beta (Aβ) plaques in the brain is a hallmark of Alzheimer's disease (AD). Detection of Aβ pathology is ...
Scientists reveal how beta-amyloid may cause Alzheimer's
Investigators at Harvard University also contributed to the study. The research, conducted in mice and in human brain tissue, may help to ...
Potential fraud in major Alzheimer's research
Aβ*56 is a form in which the beta-amyloid protein, the substance that is found forming plaques in the brains of Alzheimer's patients and which, ...