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Novel strategies for the formulation and processing of poorly water ...


Novel strategies for the formulation and processing of poorly water ...

This article provides an overview on some of the current approaches for the formulation of poorly water-soluble drugs with a special focus on strategies ...

Novel strategies for the formulation and processing of poorly water ...

Novel strategies for the formulation and processing of poorly water‐soluble drugs · K. Göke, T. Lorenz, +8 authors. A. Kwade · Published in European journal of…

Novel Strategy for the Formulation of Poorly Water-Soluble Drugs

Methods: The formulation of the microparticles was based on the emulsification/internal gelation methodology with modification4. First, a water ...

Novel strategies for the formulation and processing of poorly water ...

Novel strategies for the formulation and processing of poorly water-soluble drugs · List of references · Publications that cite this publication.

NOVEL STRATEGIES FOR POORLY WATER SOLUBLE DRUGS

These processes are used to reduce the primary particle size of poorly water soluble drugs and form stable formulations that are readily wetted and have high ...

Novel manufacturing strategies for poorly water-soluble drugs

Further, with the advances in additive manufacturing processes, 3D printing personalized medicine, rapid prototyping of formulations, and added versatility of ...

Novel formulation strategies to overcome poorly water soluble ...

The solubility increases, achieved by prodrugs or salt formation for example, are traditionally measured using the shake-flask method. This thesis investigated ...

NOVEL STRATEGIES FOR POORLY WATER SOLUBLE DRUGS

Liquisolid compact technique is a novel and most promising technology that can enhance the dissolution rate of water insoluble drugs.

Nanonization strategies for poorly water-soluble drugs

(2008) Drug nanocrystals for the formulation of poorly soluble drugs and ... (2008) A novel bottom-up process to produce drug nanocrystals: controlled ...

Formulation Strategies to Improve the Bioavailability of Poorly ...

Poorly water-soluble drug candidates are becoming more prevalent. It has been estimated that approximately 60–70% of the drug molecules are insufficiently ...

Drug Delivery Strategies for Poorly Water-Soluble Drugs | Wiley

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to ...

Formulating Poorly Water Soluble Drugs - Google Books

... methods, and regulatory considerations pertaining to ... Miller specializes in formulation and processing technologies for improving oral bioavailability of ...

Enhancing delivery of poorly water-soluble drugs by innovative ...

Thus, novel utilization of excipients and processing methods is necessary to continually expand the formulation design space. Furthermore, the development ...

Solubility Enhancement: Novel Approaches To Rational Formulation ...

Poorly water-soluble molecules account for around 40% of pharmaceuticals with market approval and almost 90% of molecules in pharma ...

Lipid-based oral formulation in capsules to improve the delivery of ...

Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical development, which is linked to their limited oral bioavailability and ...

Novel Formulation Strategies for Enhancing Dissolution and/or Oral ...

Various formulation strategies have been employed in the past to enhance the dissolution and subsequent oral absorption of poorly water-soluble drugs, such as ...

Drug Delivery Strategies for Poorly Water‐Soluble Drugs

... formulation strategies for hydrophobic drugs, including liposome ... novel applications, scale-up considerations and regulatory issues ...

Nanosuspension: A Formulation Technology for Tackling the Poor ...

Abstract:The poor water solubility of numerous novel ... water-soluble drugs: Recent advances in formulation strategies and pharmaceutical product features.

Drug Delivery Strategies for Poorly Water-Soluble Drugs - Wiley-VCH

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients ...

Novel Approaches & Techniques for Solubility Enhancement of ...

The solubility enhancement of poorly water-soluble drugs presents a significant challenge in pharmaceutical formulation. Thanks to a scientific progress and ...