O|GlcNAcylation regulates the methionine cycle to promote ...

O-GlcNAcylation regulates the methionine cycle to promote ... - PNAS

In this study, we identified AHCY, an important enzyme involved in the methionine metabolism, as a key player in the maintenance of stem cell identity.

O-GlcNAcylation regulates the methionine cycle to promote ...

Methionine metabolism is critical for the maintenance of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) pluripotency ...

O-GlcNAcylation regulates the methionine cycle to ... - NASA ADS

O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells ... Among them, the metabolism of methionine, an essential amino acid ...

(PDF) O-GlcNAcylation regulates the methionine cycle to promote ...

Methionine metabolism is critical for the maintenance of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) pluripotency.

O-GlcNAcylation regulates the methionine cycle to promote ...

O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells. by Qiang Zhu, Xuejun Cheng, Yaxian Cheng, Junchen Chen, Huan Xu, ...

O-GlcNAcylation regulates the methionine cycle to promote ...

Methionine metabolism is critical for the maintenance of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) pluripotency.

O-GlcNAcylation regulates the methionine cycle to promote ... - OUCI

Methionine metabolism is critical for the maintenance of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) pluripotency.

O-GlcNAcylation regulates the methionine cycle to ... - Altmetric

O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells · Proceedings of the National Academy of Sciences of the United States of ...

O-GlcNAcylation regulates the methionine cycle to promote ... - X-MOL

O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells [Biochemistry]. Proc. Natl. Acad. Sci. U.S.A.. Pub Date : 2020-04-07. DOI ...

The role of O-GlcNAcylation in development

O-GlcNAcylation regulates the methionine cycle to promote · pluripotency of stem cells. Proc. Natl. Acad. Sci. USA 117, 7755-7763. doi:10. 1073/pnas ...

O-GlcNAcylation: the sweet side of epigenetics

O-GlcNAcylation helps regulate gene expression by (1) changing the properties of transcription factors (localization, stability, DNA binding, ...

Growing and dividing: how O-GlcNAcylation leads the way

The nutrient-sensing posttranslational modification, O-GlcNAc, regulates the cell cycle allowing one central control point directing progression of the cell ...

Stemness of Normal and Cancer Cells: The Influence of Methionine ...

AHCY undergoes T136 O-GlcNAcylation, which promotes its activity by increasing its tetrameric assembly and its affinity with Hcy [8]. Inducing ...

Article Methionine metabolism regulates pluripotent stem cell ...

Pluripotent stem cells (PSCs) exhibit a unique feature that requires S-adenosylmethionine (SAM) for the maintenance of their pluripotency.

SYVN1-MTR4-MAT2A Signaling Axis Regulates Methionine ...

Conclusion: In summary, methionine restriction leads to increased ubiquitination of MTR4, which promotes the transfer of MAT2A mRNA out of the nucleus and MAT2A ...

Unveiling the methionine cycle: a key metabolic signature and ...

ESCC cells readily harness exogenous methionine to generate S-adenosyl-methionine (SAM), thus promoting cell proliferation. Mechanistically, ...

O-GlcNAc signaling increases neuron regeneration through one ...

In addition, supplementation in wild type with the metabolite, L-methionine (product of metr-1), which increases OCM, phenocopied the enhance ...

Methionine regulates self-renewal, pluripotency, and cell death of ...

Methionine metabolism is closely related with self-renewal, pluripotency, and cell death in GICs through modification of cholesterol biosynthesis.

Bioinformatic prediction of putative conveyers of O-GlcNAc ...

Protein O-GlcNAcylation is a dynamic posttranslational modification that is catalyzed by the enzyme O-GlcNAc transferase (OGT) and is ...

Direct stimulation of de novo nucleotide synthesis by O-GlcNAcylation

OGT still regulates PRPS1 activity in AMPK-deficient cells. Elevated PRPS1 O-GlcNAcylation promotes tumorigenesis and confers resistance to ...