Omics Views of Mechanisms for Cell Fate Determination in Early ...

During mammalian preimplantation development, a totipotent zygote undergoes several cell cleavages and two rounds of cell fate determination, ...

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Omics Views of Mechanisms for Cell Fate Determination in Early ...

Although the lineage segregation of the inner cell mass (ICM) and trophectoderm (TE) is the first symbol of cell differentiation, several molecules have been ...

Omics Views of Mechanisms for Cell Fate Determination ... - Altmetric

Omics Views of Mechanisms for Cell Fate Determination in Early Mammalian Development · Genomics, Protenomics & Biooinformatics, April 2023 · 10.1016/j.gpb.2023.03 ...

Papers - Beijing Institute of Genomics

Papers · Home / 资源库 / Papers. Papers. Omics Views of Mechanisms for Cell Fate Determination in Early Mammalian Development. Authors：, Ju, L. F., Xu, H. J. ...

Revealing Dynamic Mechanisms of Cell Fate Decisions From Single ...

While cellular processes such as proliferation, differentiation, and reprogramming are governed by complex gene regulatory programs, each cell makes its own ...

Omics Views of Mechanisms for Cell Fate Determination ... - Altmetric

Omics Views of Mechanisms for Cell Fate Determination in Early Mammalian Development · Mentioned by · Citations · Readers on.

Deciphering driver regulators of cell fate decisions from single-cell ...

Single-cell technologies enable the dynamic analyses of cell fate mapping. However, capturing the gene regulatory relationships and ...

Canalizing kernel for cell fate determination - Oxford Academic

To systematically identify master regulators and decipher the underlying mechanism of the resulting cell fate change after controlling the ...

Cell Fate Determination - an overview | ScienceDirect Topics

It is an evolutionarily conserved pathway involved in cell fate determination, self-renewal, and differentiation processes during the embryonic development ...

Single-cell multi-omics and lineage tracing to dissect cell fate ...

Understanding, predicting, and manipulating cell fate has been a long-sought goal of developmental and regenerative biology. Recent insights ...

Accessible chromatin reveals regulatory mechanisms underlying ...

... fate determination. Our research provides an intriguing insight into evolution of cell-fate decision during early embryogenesis among organisms.

Single-cell multi-omics and lineage tracing to dissect cell fate ...

Waddington's landscape and cell fates during cellular differentiation. (A) Waddington's landscape with the marble representing a cell to take on a set of ...

Decoding the mechanisms underlying cell-fate decision-making ...

The findings demonstrate that the functions of the stemness GRN is mainly determined by its well-evolved network topology rather than by ...

The first cell fate decision in pre-implantation mouse embryos

28 Citations · Omics Views of Mechanisms for Cell Fate Determination in Early Mammalian Development · Asymmetric expression of maternal mRNA governs first cell‐ ...

Cell-Fate Determination from Embryo to Cancer Development - MDPI

Elucidation of the genomic mechanism that guides the cell-fate change is one of the fundamental issues of biology. We previously demonstrated that whole ...

How a cell decides its own fate: a single-cell view of molecular ...

Recently developed single-cell omics techniques have started to provide an unprecedented, comprehensive view of the molecular changes during cell-type ...

Stem cell fate determination through protein O-GlcNAcylation

The intricate balance between self-renewal and differentiation is governed by developmental signals and cell-type-specific gene regulatory mechanisms. A ...

Cell Fate Decision Making through Oriented Cell Division - MDPI

The ability to dictate cell fate decisions is critical during animal development. Moreover, faithful execution of this process ensures proper tissue ...

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene ...

We also conducted an analysis of two published single-cell gene expression data, which were observed during the development of mouse embryos [ 44] and the ...