PDGF and cardiovascular disease

PDGF and cardiovascular disease - PubMed

Platelet-derived growth factor (PDGF) was identified in a search for serum factors that stimulate smooth muscle cell (SMC) proliferation.

PDGF and cardiovascular disease - ScienceDirect.com

While this volume clearly documents the potential role of PDGF in various developmental and disease processes, data from multiple studies support the original ...

PDGF/PDGFR Signaling in Cardiovascular Disease

cardiovascular diseases. Keywords: PDGF/PDGFR signaling; Cardiovascular disease; Atherosclerosis; Cardiac fibrosis. Jing Wang, Dongcheng Cai ...

PDGF-C and PDGF-D signaling in vascular diseases and animal ...

Current studies have shown important implications of PDGF-C and PDGF-D signaling in fibrosis, neovascularization, atherosclerosis and restenosis.

Role of PDGF-A/B Ligands in Cardiac Repair After Myocardial ...

PDGFs are key signaling molecules and important drug targets in the treatment of cardiovascular disease as multiple researchers have shown that delivery of ...

Full article: The prediction value of platelet-derived growth factor for ...

The value of plasma Platelet-Derived Growth Factor (PDGF) as a biomarker in predicting major adverse cardiovascular events (MACEs) in ...

Platelet-Derived Growth Factor D Induces Cardiac Fibrosis and ...

PDGF-D induced proliferation of interstitial fibroblasts, leading to extensive deposition of collagen. This caused a progressive dilation of the ...

The role of PDGF-BB in the bone-vascular relationship during aging

PDGF-BB has been widely implicated in cardiovascular pathogenesis, including atherosclerosis, pulmonary arterial hypertension, diabetes, ...

PDGF-D gene polymorphism is associated with increased ...

We report here for the first time that the genotypes G/A or A/A of the SNP rs974819 near PDGF-D exhibited a 2.7 fold increased cardiovascular ...

PDGF and cardiovascular disease - ASU Library Catalog

Platelet-derived growth factor (PDGF) was identified in a search for serum factors that stimulate smooth muscle cell (SMC) proliferation.

Targeting the platelet‐derived growth factor signalling in ...

... vascular inflammation and remodelling? (ii) What are the major mediators to regulate PDGF expression in a specific cardiovascular disease?

Abstract || Clinics In Surgery

On the other hand, aberrant activation of PDGF/PDGFR signaling pathway drives the progression of cardiovascular diseases such as atherosclerosis, transplant ...

A New Therapeutic Opportunity for Treating Cardiac Fibrosis ...

Recently, this group showed that PDGF-AB improved cardiac function, vascular remodeling, and scar alignment 28 days after MI in a pig model.

Platelet-Derived Growth Factor D Induces Cardiac Fibrosis and ...

Transgenic PDGF-D stimulates proliferation of cardiac interstitial fibroblasts and arterial vSMCs. This results in cardiac fibrosis followed by dilated ...

The prediction value of platelet-derived growth factor for major ...

Background: The value of plasma Platelet-Derived Growth Factor (PDGF) as a biomarker in pre- dicting major adverse cardiovascular events ...

PDGF/PDGFR Signaling in Cardiovascular Disease

The contemporary biomedical knowledge on the role of PDGF/PDGFR signaling and related mechanisms in promoting cardiovascular diseases is reviewed.

PDGF and cardiovascular disease. - Abstract - Europe PMC

Different genetic manipulations in vascular cells combined with various inhibitory strategies have provided strong evidence for PDGF playing a prominent role in ...

PDGFRβ signalling regulates local inflammation and synergizes ...

Intriguingly, increased PDGFRβ signalling promotes advanced plaque formation at novel sites in the thoracic aorta and coronary arteries. However ...

derived growth factor signalling in cardiovascular disease

9 PDGFs, mainly produced by endothelial cells, activated macrophages and smooth muscle cells, are stored and released by platelets upon activation. For. PDGF ...

Linkage between elevated PDGF-C expression and myocardial ...

They also support the growth of connective tissue and the production of extracellular matrix. ... Thus, PDGF receptor activation in the heart is ...