Paired Tumor|Germline Testing as a Driver in Better Cancer Care

Paired Tumor-Germline Testing as a Driver in Better Cancer Care

Paired testing provides important information about a patient's cancer and its treatment and can address hereditary issues of importance to the patient's ...

Paired Tumor-Germline Testing as a Driver in Better Cancer Care

Paired Tumor-Germline Testing as a Driver in Better Cancer Care.

(PDF) Paired Tumor-Germline Testing as a Driver in Better Cancer ...

PDF | On May 2, 2022, John W Henson published Paired Tumor-Germline Testing as a Driver in Better Cancer Care | Find, read and cite all the research you ...

Paired Tumor-Germline Testing as a Driver in Better Cancer Care

InvitedCommentary | Oncology. Paired Tumor-Germline Testing as a Driver in Better Cancer Care. John W. Henson, MD. Yap et al1 provide an ...

Paired Tumor-Germline Testing as a Driver in Better Cancer Care ...

Paired Tumor-Germline Testing as a Driver in Better Cancer Care. John W. Henson. Research output: Contribution to journal › Comment/debate › peer-review.

Universal Germline and Tumor Genomic Testing Needed to Win the ...

Moreover, relatives who are not carriers need not have the apprehension about cancer risk. Furthermore, a combined tumor and germline multigene testing strategy ...

Paired tumor-germline testing can enhance patient care—with ...

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Aligning Germline Cancer Predisposition With Tumor-Based Next ...

E318K) are filtered off using some somatic test results, even in the absence of a paired normal test, because they may be less likely to be driving cancer ...

Genetic Testing Empowers Better Cancer Care, Prevention, and ...

Paired testing of a tumor with surrounding normal tissue or concur-rent testing of white blood cells will examine not just somatic tumor gene ...

communicating biomarker test results - ACCC Cancer

laboratories perform paired somatic-germline testing (also ... 2022.13070. 4. Henson JW. Paired tumor-germline testing as a driver in better cancer care.

Paired Tumor-Germline Testing as a Driver in Better Cancer Care

Paired Tumor-Germline Testing as a Driver in Better Cancer Care · List of references · Publications that cite this publication.

Testing to identify genomic variants related to cancer

The goal of somatic testing is to identify options for genome-informed treatment. Paired somatic-germline testing (also called tumor-normal) assesses variants ...

Aligning Germline Cancer Predisposition With Tumor-Based Next ...

Pros and cons of tumor-only versus paired tumor-normal genetic testing. ... tests to guide cancer treatment: Results from a nationally ...

Germline and somatic testing for homologous repair deficiency in ...

We argue for the widespread adoption germline testing for all patients at the time of prostate cancer (PCa) diagnosis. Patients with metastatic ...

Interpreting and integrating genomic tests results in clinical cancer ...

Although genomic tests can lead to better outcomes by informing cancer risk, prognosis, and therapeutic selection, they remain underutilized in ...

Germline Findings Among Tumors From Cancer Types Lacking ...

Tumor molecular profiling via next-generation sequencing to identify genomic drivers is now commonly used in guiding treatment selection in ...

germline vs somatic testing for cancer: hereditary cancer syndromes

However, unless the paired testing is clinically validated to identify germline ... Paired tumor-germline testing as a driver in better cancer care. JAMA Netw ...

Genetic Counseling and Germline Testing in the Era of Tumor ...

Current guidelines for cancer genetic testing may miss clinically actionable germline changes, which may have important implications for cancer ...

Insights for precision oncology from the integration of genomic and ...

A single test such as WGS, comprising paired tumor-normal sequencing, can facilitate the concurrent detection of somatic small variants ...

Paired tumor sequencing and germline testing in breast cancer ...

Combining germline and somatic sequencing (paired testing) offers an advantage over a single technique approach. Our study evaluates the role of paired testing.