Pancreas pathology in type 1 diabetes

Pancreas pathology in type 1 diabetes: an evolving story - PubMed

We review the current knowledge of pancreas pathology in type 1 diabetes. During the last two decades, dedicated efforts toward the recovery ...

100 YEARS OF INSULIN: Pancreas pathology in type 1 diabetes

The main pathological abnormalities observed in the pancreas with type 1 diabetes are beta-cell loss and insulitis; more recently, hyperexpression of HLA class ...

Pancreas pathology in type 1 diabetes - Journal of Endocrinology

The main pathological abnormalities observed in the pancreas with type 1 diabetes are beta-cell loss and insulitis; more recently, hyperexpression of HLA class ...

Under the Microscope - Type 1 Diabetes - Johns Hopkins Pathology

The Pathology of Type 1 Diabetes · 1) Antigen Presenting Cells (APCs) are exposed to insulin producing cells in the pancreas · 2) These APCs travel to the lymph ...

Pancreas Pathology During the Natural History of Type 1 Diabetes

Recent studies of pancreata from organ donors with T1D and non-diabetic donors expressing T1D-associated autoantibodies reveal pathological ...

Type 1 diabetes in the pancreas: A histological perspective - Leete

Type 1 diabetes is first and foremost an autoimmune-mediated disease of the pancreas and imparts a huge burden on people living with the ...

Type 1 diabetes mellitus as a disease of the β-cell (do not ... - Nature

Type 1 diabetes mellitus is believed to result from destruction of the insulin-producing β-cells in pancreatic islets that is mediated by autoimmune mechanisms.

Pancreas Pathology in Type 1 Diabetes: An evolving Story Short title

The main pathological abnormalities observed in the pancreas with type 1 diabetes are beta cell loss, insulitis, and more recently hyperexpression of HLA class ...

Pancreas Pathology During the Natural History of Type 1 Diabetes

Pancreas pathology evolves through disease stages, is asynchronous, and demonstrates a chronic disease that remains active years after diagnosis.

Different Patterns of Fibrosis, Metaplasia, Angiopathy, and Adiposity

Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.

Fifty years of pancreatic islet pathology in human type 1 diabetes

This review provides a summary of some of the insights gained from these studies and highlights areas of ongoing uncertainty.

Pancreas - Diabetes mellitus - Pathology Outlines

Type 1: inconsistent reduction in number and size of islets, uneven insulinitis (T lymphocytes) · Type 1: early insulinitis with marked islet ...

Increased Immune Cell Infiltration of the Exocrine Pancreas

Type 1 diabetes (T1D) is a complex chronic disorder in which the pancreatic insulin-producing β-cells are destroyed by the immune system (1).

Substance Use Affects Type 1 Diabetes Pancreas Pathology

Alcohol and/or cocaine use in type 1 diabetes organ donors increases exocrine pancreas pathology and islet amyloid deposition but does not affect insulitis or ...

Pancreatic Pathology in Type 1 Diabetes Mellitus - Semantic Scholar

This review summarises the knowledge of the pathology of the endocrine pancreas in human type 1 diabetes and explores the progression of this understanding ...

Pancreas Pathology During the Natural History of Type 1 Diabetes.

Pancreas pathology evolves through disease stages, is asynchronous, and demonstrates a chronic disease that remains active years after diagnosis. Critically, β- ...

Pancreas Pathology During the Natural History of Type 1 Diabetes

Purpose of review We provide an overview of pancreas pathology in type 1 diabetes (T1D) in the context of its clinical stages.

Pancreas Pathology During the Natural History of Type 1 Diabetes

C-peptide decline in type 1 diabetes has two phases: an initial exponential fall and a subsequent stable phase. Diabetes Care, 2018. 41(7):1486–92. This study ...

Pancreatic pathology in type 1 diabetes mellitus

This review summarises our knowledge of the pathology of the endocrine pancreas in human type 1 diabetes and, in particular, explores the progression of this ...

Pancreatic pathology in type 1 diabetes - Media Centre

Pancreatic pathology in type 1 diabetes. Session: Insulin secretion in type 1 diabetes. 60th EASD Annual Meeting. Cairo Hall. 12. September 2024 17:50 - 18:10.