Patient|Derived Organoids Predict Chemoradiation Responses of ...

Patient-Derived Organoids Predict Chemoradiation Responses of ...

Accumulating evidence indicates that patient-derived organoids (PDOs) can predict drug responses in the clinic, but the ability of PDOs to ...

Patient-Derived Organoids Predict Chemoradiation Responses of ...

Our co-clinical trial data confirm that rectal cancer organoids (RCOs) closely recapitulate the pathophysiology and genetic changes of corresponding tumors.

Patient-Derived Organoids Predict Chemoradiation Responses of ...

generated a patient-derived organoid (PDO) biobank from patients with locally advanced rectal cancer. (LARC) and reported that organoids had.

Patient-derived tumor organoids predict responses to irinotecan ...

Patient-derived tumor organoids predict responses to irinotecan-based neoadjuvant chemoradiotherapy in patients with locally advanced rectal ...

Patient-derived organoids as a predictive biomarker for treatment ...

Since 2018, 17 publications have examined PDOs as a potential predictive biomarker in the treatment of cancer patients. We review and provide a ...

Patient-derived organoids can predict response to chemotherapy in ...

We developed an in vitro test based on patient-derived tumor organoids (PDOs) from metastatic lesions to identify nonresponders to standard-of-care ...

Patient-derived organoids as individual patient models for ...

Patient-derived esophageal and rectal tumor organoids have great potential to predict chemoradiotherapy responses. •. The clinical implementation of patient- ...

Patient-Derived Cancer Organoids as Predictors of Treatment ...

Organoids were able to predict the response to irinotecan-based therapies in more than 80% of patients without misclassifying patients who ...

Patient-derived organoids predict chemotherapy response - Nature

An in vitro test based on patient-derived tumour organoids from metastatic lesions accurately predicted response to irinotecan monotherapy or 5- ...

The Efficacy of Using Patient-Derived Organoids to Predict ... - MDPI

Tumour organoids are promising models for personalised medicine in the context of selecting chemotherapy and radiotherapy options. Further advancements in ...

Advances of Patient-Derived Organoids in Personalized Radiotherapy

Patient-derived organoids (PDO), based on the advanced three-dimensional (3D) culture technology, can provide more relevant physiological and ...

Patient‐Derived Organoids from Colorectal Cancer with Paired Liver ...

The chemosensitivity data in vitro reveal the potential value of clinical application for PDOs to predict chemotherapy response (FOLFOX or ...

Patient-derived Organoid Model for Predicting the Chemoresponse ...

The response of the patients' organoids to chemotherapeutic agents was consistent with the response to chemotherapy actually performed in those patients with ...

Patient-Derived Organoids Predict Chemoradiation Responses of ...

Accumulating evidence indicates that patient-derived organoids (PDOs) can predict drug responses in the clinic, but the ability of PDOs to predict responses ...

Patient-Derived Tumor Organoids Can Predict the Progression-Free ...

Recent studies have shown patient-derived tumor organoids can predict the drug response of patients with cancer. However, the prognostic value of patient- ...

The responses of individual organoid to different treatments

... (irradiation, 5-Fu and CPT-11): data for Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer.

Patient-derived organoids as individual patient models for ...

Semantic Scholar extracted view of "Patient-derived organoids as individual patient models for chemoradiation response prediction in gastrointestinal ...

Patient-derived organoids help predict how patients respond to ...

In a prospective clinical trial, their organoid-based test predicted responses in 80% of patients treated with the standard therapy irinotecan.

Patient-derived organoids can predict response to chemotherapy in ...

Request PDF | Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients | There is a clear and unmet clinical ...

Patient-Derived Organoids Predict Chemoradiation Responses of ...

Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer ... Authors: Ye Yao; Xiaoya Xu; Lifeng Yang; Ji Zhu; Juefeng Wan ...