Patient|Derived Organoids Show Promise for Personalized Therapy ...

Patient-derived organoids: a promising model for personalized ...

PDOs are 3D in vitro models; many studies have shown that they can recapitulate basic features of primary tumors, including histological complexity and genetic ...

Patient-Derived Organoids Show Promise for Personalized Therapy ...

Patient-derived organoids (PDOs) may possess the potential to personalize therapy and allow for the exclusion of ineffective drugs from ...

Unlocking the potential of patient-derived organoids ... - UCLA Health

“Testing drugs with patient-derived tumor organoids has potential to help predict how a patient may respond to treatment, with the goal of ...

Patient-derived organoids: Transforming cancer research and ...

Patient-derived organoids (PDOs) are revolutionizing cancer research, enhancing drug testing and personalized treatment through advanced 3D ...

Patient-derived organoids as a predictive biomarker for treatment ...

Effective predictive biomarkers are needed to enable personalized medicine and increase treatment efficacy and survival for cancer patients, ...

Advances of Patient-Derived Organoids in Personalized Radiotherapy

Patient-derived organoids (PDO), based on the advanced three-dimensional (3D) culture technology, can provide more relevant physiological ...

Review Patient-derived organoids in precision cancer medicine

In summary, as preclinical models, organoids hold potential for clinical application. They enhance the efficiency and precision of drug ...

Patient-derived organoids for precision oncology - BMC Cancer

Ovarian and breast cancer patients' organoids showed heterogeneity in drug resistance and sensitivity. iPSCs-derived cardiomyocytes, hepatocytes ...

Patient‐Derived Organoids Can Guide Personalized‐Therapies for ...

Personalized therapies are urgently needed for patients with advanced breast cancers. Patient-derived organoids (PDOs) can be generated from ...

Patient-derived tumor organoids: a new avenue for preclinical ...

Organoid biobanks exhibit promises for identifying new therapeutic strategies, guiding the use of molecules in development, and drug repurposing ...

Patient-derived organoids in cancer research and treatment

This is why Hans Clevers defines organoids as Next Generation Diagnosis (NGD). While PDOs hold immense promise in cancer research and personalized medicine, ...

Patient-derived organoids in precision cancer medicine: Med

Subsequently, the chip was used to simulate differential clinical treatment responses among patients with variations in drug resistance. Drug ...

Establishment of patient‐derived organoids for guiding personalized ...

What's new? Heterogeneity in breast cancer contributes to variations in treatment effectiveness. Patient-derived organoids (PDOs) have ...

The future of cancer therapy: exploring the potential of patient ...

Patient-derived organoids (PDOs) have emerged as a groundbreaking tool in oncology research (Sachs and Clevers, 2014), offering three- ...

Promises and challenges of organoid-guided precision medicine: Med

As such, patient-derived organoid (PDO) platforms provide an unprecedented opportunity for improving preclinical drug discovery, clinical trial validation, and, ...

Patient-Derived Organoids: Promises, Hurdles and Potential Clinical ...

PDOs can be established from primary and metastatic cancer deposits. PDOs model the parental tissue and can be used to (a) complement standard ...

Patient-derived organoid (PDO) platforms to facilitate clinical ...

Showing numerous advantages over 2D cell lines, 3D cell lines, and primary cell culture, organoids have been applied in drug screening to ...

Medium-throughput Drug Screening of Patient-derived Organoids ...

Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy.

Patient‐Derived Organoids Can Guide Personalized‐Therapies for ...

Patient‐Derived Organoids Can Guide Personalized‐Therapies for Patients with Advanced Breast Cancer · Ping Chen, Xu Zhang, +31 authors. Chuxia Deng · Published in ...

Patient-derived organoids in human cancer: a platform for ...

In short, the advancements in tumor organoid technology hold significant promise in enhancing the efficacy and precision of in vitro drug ...