Pharmacogenetics at scale in real|world bioresources

Pharmacogenetics at scale in real-world bioresources

This study utilizes the UK Biobank dataset, including 10 365 patients treated with clopidogrel, to offer the largest observational analysis of these ...

CYP2C19 and clopidogrel outcomes in UK Biobank - PubMed

Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank. Pharmacogenet Genomics. 2024 Apr 1;34(3):73-82. doi: ...

CYP2C19 and clopidogrel outcomes in UK Biobank — Discovery

Dive into the research topics of 'Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank'. Together they form a ...

Pharmacogenetics at scale in real-world bioresources: CYP2C19 ...

PharmGKB annotates drug labels containing pharmacogenetic information from multiple drug regulatory agencies. Labels from the FDA, EMA and HCSC are updated ...

CYP2C19 and clopidogrel outcomes in UK Biobank - ResearchGate

Request PDF | Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank | Objective The impact of CYP2C19 ...

Pharmacogenetics at scale in real-world bioresources: CYP2C19 ...

Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank. Khaled Bedair, Blair H. Smith, Colin Palmer, Alexander ...

Pharmacogenetics at scale in real-world bioresources: CYP2C19 ...

Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank. Pharmacogenetics and genomics. 2024.

April 2024 - Volume 34 - Issue 3 : Pharmacogenetics and Genomics

Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank. Bedair, Khaled F.; Smith, Blair; Palmer, Colin N.A. ...

Pharmacogenetics at Scale: An Analysis of the UK Biobank - PubMed

Pharmacogenetics (PGx) studies the influence of genetic variation on drug response. Clinically actionable associations inform guidelines created by the ...

Biobank scale pharmacogenomics informs the genetic ... - medRxiv

Until recently, PGx loci could not be studied at biobank scale. Here we analyze PGx haplotype variation to detect associations with medication ...

Real-World Impact of a Pharmacogenomics-Enriched ...

However, few studies testing these tools at scale, using relevant system-wide metrics, and under real-world conditions, have been published ...

From pharmacogenetics to pharmaco-omics: Milestones and future ...

Zand, et al. Variants in STAU2 associate with metformin response in a type 2 diabetes cohort: a pharmacogenomics study using real-world electronic health record ...

Evaluating the frequency and the impact of pharmacogenetic alleles ...

Pharmacogenetics at scale: an analysis of the UK Biobank. Clin ... real-world healthcare system. J Pers Med. 2021;11(12):1242. Article ...

Using pharmacogenomics to improve patient outcomes

One example is the pan-European Ubiquitous. Pharmacogenomics consortium, which implemented real-world pharmacogenomic testing within a prospective ...

Pharmacogenetics at scale: An analysis of the UK Biobank - bioRxiv

Abstract. Pharmacogenetics (PGx) studies the influence of genetic variation on drug response. Clinically actionable associations inform ...

The history and future of pharmacogenetics in Aotearoa/New Zealand

This would have enabled provision of real-time prescribing support based on the pharmacogenetic profile of a patient. ... Pharmacogenetics at Scale: An Analysis ...

: Publications catalogue - UK Biobank

Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank, Khaled F. Bedair (+4), 2023, Pharmacogenetics and Genomics.

4 Business Models That Support Bioresource Discovery and ...

... world, said Lynn Matrisian, the vice president of science and medical affairs ... The availability of data generated from large-scale genetic bioresources ...

Pharmacogenetics - an overview | ScienceDirect Topics

Initially, the term was used in respect of variations in drug metabolizing enzymes, but it has now been expanded to include polymorphisms in drug receptor, drug ...

Pharmacogenetics Clinical Decision Support Systems for Primary ...

The overall aim was to better understand perceived barriers to the real-world implementation of pharmacogenetics and identify strategies that ...