Pharmacogenetics of antihypertensive treatment

Pharmacogenetics of antihypertensive treatment: detailing ...

Hypertension pharmacogenetics seeks to find genetic predictors of response to drugs that lower blood pressure and to translate this knowledge into clinical ...

Pharmacogenetics of antihypertensive drug responses - PubMed

The blood pressure (BP) response to any single antihypertensive drug is characterized by marked interindividual variation, and the known predictors of ...

Pharmacogenetics of antihypertensive treatment - ScienceDirect.com

More than forty studies have investigated associations between genetic polymorphisms and response to antihypertensive drugs.

Pharmacogenetics of Antihypertensive Response | Hypertension

The widespread variation in individual response to antihypertensive treatment motivates a search for genetic factors associated with this ...

Pharmacogenomics of Hypertension Treatment - MDPI

This article reviews the recent pharmacogenomics literature concerning the key classes of antihypertensive drugs currently in use.

Hypertension pharmacogenomics: in search of personalized ...

The long-term goal of hypertension pharmacogenomics is to use genetic and clinical information to select the antihypertensive drug regimen that ...

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo ...

Recent extensive genome‐wide association studies have revealed >40 genetic loci associated with essential hypertension,,, but even combined they ...

The Future of Pharmacogenetics in the Treatment of Hypertension

Pharmacogenetics research has found that multiple genetic variants have a modest influence on individual response to different antihypertensive medications.

Pharmacogenomics of Hypertension and Preeclampsia - Frontiers

Pharmacogenomics may help to guide the personalized treatment for non-responsive hypertensive patients. There is evidence for the association of ...

Pharmacogenetics of antihypertensive treatment - Wiley Online Library

The goals of hypertension pharmacoge- netics are to apply knowledge of genetic predictors of the treatment response to drugs that lower blood pressure and to ...

Personalized antihypertensive treatment guided by ...

A genome-wide association study (GWAS) involving over 60,000 cases identified polymorphisms of ADRB1 and CYP2D6 associated with hypertension and ...

Pharmacogenomics And Hypertension: Current Insights | PGPM

Diuretics are the first-line drugs of choice for most patients with hypertension. Their mechanism of action involves the increases in sodium ...

Pharmacogenomic approaches to study the effects of ... - Nature

Pharmacogenomic studies aim to clarify the role of various genes and their variations in relation to the effects of antihypertensive drugs.

Pharmacogenomics of antihypertensive drugs: Rationale and ...

Conclusions. Pharmacogenetic-guided therapy holds clinical potential for hypertension, but the literature in the field is limited. This trial will add ...

Advancing management of hypertension through pharmacogenomics

Conceptually, the goal of hypertension pharmacogenomics is to be able to utilize genetic information, along with other pertinent clinical or demographic data, ...

Pharmacogenetics of antihypertensive drug response - SpringerLink

Pharmacogenetics is a discipline of molecular medicine that investigates the genetic basis of individual variation of drug responses. Before the era of the.

Pharmacogenetics of antihypertensive treatment - Wiley Online Library

Abstract Hypertension is a common disorder associated with increased cardiovascular morbidity and mortality. Unfortunately, in the United ...

Exploring Pharmacogenetic Testing for Hypertension Management ...

PGx is experiencing accelerated growth in China, providing an opportunity to engage young individuals with hypertension in primary healthcare settings.

Pharmacogenetics of Antihypertensive Treatment - Medscape

Antihypertensive pharmacogenetics (and pharmacogenomics - the whole-genome application of pharmacogenetics) holds the promise of reducing clinicians' dependence ...

Pharmacogenetic association of the NR1H3 promoter variant with ...

The associations of 11 candidate variants with blood pressure changes in response to antihypertensive drugs and with the risk of cardiovascular ...